M
Michael A. Owston
Researcher at Texas Biomedical Research Institute
Publications - 31
Citations - 350
Michael A. Owston is an academic researcher from Texas Biomedical Research Institute. The author has contributed to research in topics: Baboon & Insulin resistance. The author has an hindex of 11, co-authored 31 publications receiving 287 citations.
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Journal ArticleDOI
Particle-to-PFU Ratio of Ebola Virus Influences Disease Course and Survival in Cynomolgus Macaques
Kendra J. Alfson,Kendra J. Alfson,Laura E. Avena,Michael W. Beadles,Hilary M. Staples,Jerritt Nunneley,Anysha Ticer,Edward J. Dick,Michael A. Owston,Christopher R. Reed,Jean L. Patterson,Ricardo Carrion,Anthony Griffiths,Anthony Griffiths +13 more
TL;DR: It is reported that serial passages of EBOV in cell culture resulted in a decrease in particle-to-PFU ratio, which suggests that some particles are unable to form a plaque in a cell culture assay but are able to result in lethal disease in vivo.
Journal ArticleDOI
Natural pathology of the Baboon (Papio spp.).
Yugendar R. Bommineni,Edward J. Dick,Adinarayana R. Malapati,Michael A. Owston,Gene B. Hubbard +4 more
TL;DR: The natural pathology of the baboon is not as well defined as other non‐human primates, but the useful animal models for biomedical research are useful and the natural pathology is not well defined.
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Diet-induced early-stage atherosclerosis in baboons: Lipoproteins, atherogenesis, and arterial compliance
Michael C. Mahaney,Genesio M. Karere,David L. Rainwater,Venkata Saroja Voruganti,Edward J. Dick,Michael A. Owston,Karen Rice,Laura A. Cox,Anthony G. Comuzzie,John L. VandeBerg +9 more
TL;DR: The purpose of this study was to determine whether dietary manipulation can reliably induce early‐stage atherosclerosis and clinically relevant changes in vascular function in an established, well‐characterized non‐human primate model.
Journal ArticleDOI
Pathology of spontaneous air sacculitis in 37 baboons and seven chimpanzees and a brief review of the literature.
TL;DR: Air sacculitis is an important clinical condition in non‐human primates and should be considered as a central nervous system disorder in humans, according to the need for further research.
Journal ArticleDOI
Correlation between presence of Trypanosoma cruzi DNA in heart tissue of baboons and cynomolgus monkeys, and lymphocytic myocarditis.
James N. Mubiru,Alice Yang,Edward J. Dick,Michael A. Owston,R. Mark Sharp,Jane F. VandeBerg,Robert E. Shade,John L. VandeBerg +7 more
TL;DR: A positive correlation between PCR positivity and lymphocytic myocarditis in both baboons and cynomolgus monkeys is shown and epicarditis is shown as a common finding in animals infected with T. cruzi.