Michael Frotscher

TL;DR: In dual whole-cell voltage recordings from pyramidal neurons, the coincidence of post Synaptic action potentials and unitary excitatory postsynaptic potentials was found to induce changes in EPSPs.

TL;DR: The results suggest that CA1 hippocampal LTP is controlled by the number or subunit composition of AMPA receptors and show a dichotomy between LTP in CA1 and acquisition of spatial memory.

TL;DR: Evidence is provided for a novel, noninvasive approach for targeting potential therapeutic factors to the central nervous system using genetically-modified hematopoietic cells enter the CNS and differentiate into microglia after bone-marrow transplantation.

TL;DR: An interneuron network model based on experimentally determined properties was able to generate oscillatory activity with higher coherence over a broad range of frequencies (20–110 Hz), and high coherence and flexibility in frequency control emerge from the combination of synaptic properties, network structure, and electrical coupling.

TL;DR: It is reported that ablation of Cajal–Retzius cells in organotypic slice cultures of hippocampus prevented the ingrowth of entorhinal but not of commissural afferents, and reelin is essential for the formation of layer-specific hippocampal connections.