M
Michael Goitein
Researcher at Harvard University
Publications - 162
Citations - 12614
Michael Goitein is an academic researcher from Harvard University. The author has contributed to research in topics: Radiation therapy & Proton therapy. The author has an hindex of 60, co-authored 162 publications receiving 12206 citations. Previous affiliations of Michael Goitein include University of Zurich.
Papers
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Journal ArticleDOI
Relative biological effectiveness (RBE) values for proton beam therapy.
Harald Paganetti,Andrzej Niemierko,Marek Ancukiewicz,Leo E. Gerweck,Michael Goitein,Jay S. Loeffler,Herman D. Suit +6 more
TL;DR: There is too much uncertainty in the RBE value for any human tissue to propose RBE values specific for tissue, dose/fraction, proton energy, etc, and experimental in vivo and clinical data indicate that continued employment of a generic RBEvalue is reasonable.
Journal ArticleDOI
Histogram reduction method for calculating complication probabilities for three-dimensional treatment planning evaluations.
TL;DR: A method of calculating complication probabilities for inhomogeneously irradiated normal tissues is presented, using examples from an NCI 3-D treatment planning contract.
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Effects of intra-fraction motion on IMRT dose delivery: statistical analysis and simulation.
TL;DR: The main effect of organ motion in IMRT is an averaging of the dose distribution without motion over the path of the motion, the same as for treatments with conventional beams.
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A pencil beam algorithm for proton dose calculations
Linda Hong,Michael Goitein,Marta Bucciolini,R. Comiskey,Bernard Gottschalk,Skip Rosenthal,Chris Serago,Marcia Urie +7 more
TL;DR: A pencil beam algorithm for proton dose calculations which takes accurate account of the effects of materials upstream of the patient and of the air gap between them and the patient is developed.
Journal ArticleDOI
Advanced prostate cancer: The results of a randomized comparative trial of high dose irradiation boosting with conformal protons compared with conventional dose irradiation using photons alone
William U. Shipley,Lynn Verhey,John E. Munzenrider,Herman D. Suit,Marcia Urie,P.L. McManus,Robert H. Young,Jenot W. Shipley,Anthony L. Zietman,Peter J. Biggs,Niall M. Heney,Michael Goitein +11 more
TL;DR: An increase in prostate tumor dose by external beam of 12.5% to 75.6 Cobalt Gray Equivalent using a conformal perineal proton boost significantly improved local control only in patients with poorly differentiated tumors.