M
Michael Holst
Researcher at University of California, San Diego
Publications - 172
Citations - 13554
Michael Holst is an academic researcher from University of California, San Diego. The author has contributed to research in topics: Finite element method & Nonlinear system. The author has an hindex of 38, co-authored 169 publications receiving 12132 citations. Previous affiliations of Michael Holst include University of California, Berkeley & California Institute of Technology.
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Journal ArticleDOI
Electrostatics of nanosystems: Application to microtubules and the ribosome
TL;DR: The application of numerical methods are presented to enable the trivially parallel solution of the Poisson-Boltzmann equation for supramolecular structures that are orders of magnitude larger in size.
Journal ArticleDOI
Improvements to the APBS biomolecular solvation software suite
Elizabeth Jurrus,Dave Engel,Keith T. Star,Kyle E. Monson,Juan Brandi,Lisa E. Felberg,David H. Brookes,Leighton Wilson,Jiahui Chen,Karina Liles,Minju Chun,Peter Li,David W. Gohara,Todd J. Dolinsky,Robert Konecny,David Ryan Koes,Jens Erik Nielsen,Teresa Head-Gordon,Weihua Geng,Robert Krasny,Guo-Wei Wei,Michael Holst,J. Andrew McCammon,Nathan A. Baker +23 more
TL;DR: The Adaptive Poisson-Boltzmann Solver (APBS) as mentioned in this paper was developed to solve the equations of continuum electrostatics for large biomolecular assemblages that has provided impact in the study of a broad range of chemical, biological, and biomedical applications.
Journal ArticleDOI
Improvements to the APBS biomolecular solvation software suite.
Elizabeth Jurrus,Dave Engel,Keith T. Star,Kyle E. Monson,Juan Brandi,Lisa E. Felberg,David H. Brookes,Leighton Wilson,Jiahui Chen,Karina Liles,Minju Chun,Peter Li,David W. Gohara,Todd J. Dolinsky,Robert Konecny,David Ryan Koes,Jens Erik Nielsen,Teresa Head-Gordon,Weihua Geng,Robert Krasny,Guo-Wei Wei,Michael Holst,J. Andrew McCammon,Nathan A. Baker +23 more
TL;DR: The Adaptive Poisson-Boltzmann Solver (APBS) as mentioned in this paper was developed to solve the equations of continuum electrostatics for large biomolecular assemblages that have provided impact in the study of a broad range of chemical, biological and biomedical applications.
Journal ArticleDOI
Multigrid solution of the Poisson-Boltzmann equation
Michael Holst,Faisal Saied +1 more
TL;DR: A multigrid method is presented for the numerical solution of the linearized Poisson–Boltzmann equation arising in molecular biophysics and results indicate that the multigrids method is superior to the preconditioned CG methods and SOR and that the advantage ofMultigrid grows with the problem size.
Journal ArticleDOI
Adaptive multilevel finite element solution of the Poisson–Boltzmann equation I. Algorithms and examples
TL;DR: It is shown that the best available uniform mesh‐based finite difference or box‐method algorithms, including multilevel methods, require substantially more time to reach a target PBE solution accuracy than the adaptive multileVEL methods in MC.