Michael Kolbe

TL;DR: A combination of ion-ion and ion-dipole interactions for stabilizing the anion 18 angstroms below the membrane surface explains why chloride and proton translocation modes are mechanistically equivalent in archaeal rhodopsins.

TL;DR: An alternative approach combining recombinant wild-type needle production, solid-state NMR, electron microscopy and Rosetta modelling is reported to reveal the supramolecular interfaces and ultimately the complete atomic structure of the Salmonella typhimurium T3SS needle.

TL;DR: It is demonstrated that AhR senses distinct bacterial virulence factors and controls antibacterial responses, supporting a previously unidentified role for AhR as an intracellular pattern recognition receptor, and identifying bacterial pigments as a new class of pathogen-associated molecular patterns.

TL;DR: Results show that the interaction of Gt with an activated rhodopsin monomer is sufficient for fully functional Gt activation, and the activation rate in solution is at the physically possible limit, but the rate in the native membrane is still 10-fold higher.

TL;DR: The assumption that homodimerization of transmembrane tight junction proteins may serve as a common structural feature in tight junction assembly is supported.