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Michael Patterson

Researcher at University of Roehampton

Publications -  80
Citations -  7847

Michael Patterson is an academic researcher from University of Roehampton. The author has contributed to research in topics: Ghrelin & Appetite. The author has an hindex of 37, co-authored 79 publications receiving 7338 citations. Previous affiliations of Michael Patterson include University of Texas Medical Branch & Imperial College London.

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Kisspeptin-54 stimulates the hypothalamic-pituitary gonadal axis in human males.

TL;DR: Kisspeptin-54 infusion significantly increased plasma LH, FSH, and testosterone concentrations compared with saline infusion and was designed to determine the effects of elevating circulating kisspeptin levels on LH,FSH,and testosterone in male volunteers.
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Attenuated peptide YY release in obese subjects is associated with reduced satiety.

TL;DR: Obese subjects have a PYY deficiency that would reduce satiety and could thus reinforce their obesity, and fasting and postprandial endogenous plasma PYY levels were attenuated in obese humans and rodents.
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Oxyntomodulin Suppresses Appetite and Reduces Food Intake in Humans

TL;DR: Elevated levels of endogenous OXM associated with disorders of the gastrointestinal tract may contribute to anorexia, and central injection of OXM reduces food intake and weight gain in rodents.
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Pancreatic polypeptide reduces appetite and food intake in humans.

TL;DR: The data demonstrates that PP causes a sustained decrease in both appetite and food intake, which suggests that PP may act as a circulating factor that regulates food intake.
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Central and peripheral administration of kisspeptin-10 stimulates the hypothalamic-pituitary-gonadal axis.

TL;DR: Kisspeptin therefore potently stimulates the hypothalamic‐pituitary‐gonadal axis and is likely to be mediated via the hypothalamate LHRH system.