M
Michael Pheasant
Researcher at University of Queensland
Publications - 17
Citations - 5499
Michael Pheasant is an academic researcher from University of Queensland. The author has contributed to research in topics: Genome & Gene. The author has an hindex of 15, co-authored 17 publications receiving 5269 citations. Previous affiliations of Michael Pheasant include Australian Research Council & University of California, Santa Cruz.
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Journal ArticleDOI
Ultraconserved Elements in the Human Genome
Gill Bejerano,Michael Pheasant,Igor V. Makunin,Stuart Stephen,W. James Kent,John S. Mattick,David Haussler +6 more
TL;DR: There are 481 segments longer than 200 base pairs that are absolutely conserved between orthologous regions of the human, rat, and mouse genomes, which represent a class of genetic elements whose functions and evolutionary origins are yet to be determined, but which are more highly conserving between these species than are proteins.
Journal ArticleDOI
The UCSC Genome Browser database: update 2010
Brooke Rhead,Donna Karolchik,Robert M. Kuhn,Angie S. Hinrichs,Ann S. Zweig,Pauline A. Fujita,Mark Diekhans,Kayla E. Smith,Kate R. Rosenbloom,Brian J. Raney,Andy Pohl,Michael Pheasant,Laurence R. Meyer,Katrina Learned,Fan Hsu,Jennifer Hillman-Jackson,Rachel A. Harte,Belinda Giardine,Timothy R. Dreszer,Hiram Clawson,Galt P. Barber,David Haussler,W. James Kent +22 more
TL;DR: The University of California, Santa Cruz Genome Browser website provides a large database of publicly available sequence and annotation data along with an integrated tool set for examining and comparing the genomes of organisms, aligning sequence to genomes, and displaying and sharing users’ own annotation data.
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The relationship between non-protein-coding DNA and eukaryotic complexity.
TL;DR: It is shown by analysis of sequenced genomes that the relative amount of non-protein-coding sequence increases consistently with complexity, and it is suggested that the informational paradox in complex organisms may be explained by the expansion of cis-acting regulatory elements and genes specifying trans-acting non- protein-c coding RNAs.
Journal ArticleDOI
The UCSC Genome Browser Database: update 2009
Robert M. Kuhn,Donna Karolchik,Ann S. Zweig,Ting Wang,Kayla E. Smith,Kate R. Rosenbloom,Brooke Rhead,Brian J. Raney,Andy Pohl,Michael Pheasant,Laurence R. Meyer,Fan Hsu,Angie S. Hinrichs,Rachel A. Harte,Belinda Giardine,Pauline A. Fujita,Mark Diekhans,Timothy R. Dreszer,Hiram Clawson,Galt P. Barber,David Haussler,W. J. Kent +21 more
TL;DR: The UCSC Genome Browser Database (GBD) is a publicly available collection of genome assembly sequence data and integrated annotations for a large number of organisms, including extensive comparative-genomic resources.
Journal ArticleDOI
ENCODE whole-genome data in the UCSC Genome Browser
Kate R. Rosenbloom,Timothy R. Dreszer,Michael Pheasant,Galt P. Barber,Laurence R. Meyer,Andy Pohl,Brian J. Raney,Ting Wang,Angie S. Hinrichs,Ann S. Zweig,Pauline A. Fujita,Katrina Learned,Brooke Rhead,Kayla E. Smith,Robert M. Kuhn,Donna Karolchik,David Haussler,W. James Kent +17 more
TL;DR: The Encyclopedia of DNA Elements (ENCODE) project is an international consortium of investigators funded to analyze the human genome with the goal of producing a comprehensive catalog of functional elements.