M
Michael Potente
Researcher at Max Planck Society
Publications - 63
Citations - 11811
Michael Potente is an academic researcher from Max Planck Society. The author has contributed to research in topics: Angiogenesis & Endothelial stem cell. The author has an hindex of 31, co-authored 57 publications receiving 10002 citations. Previous affiliations of Michael Potente include Max Delbrück Center for Molecular Medicine & Humboldt University of Berlin.
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Journal ArticleDOI
Basic and Therapeutic Aspects of Angiogenesis
TL;DR: The emerging principles of vascular growth provide exciting new perspectives, the translation of which might overcome the current limitations of pro- and antiangiogenic medicine.
Journal ArticleDOI
MicroRNA-92a Controls Angiogenesis and Functional Recovery of Ischemic Tissues in Mice
Angelika Bonauer,Guillaume Carmona,Masayoshi Iwasaki,Marina Mione,Masamichi Koyanagi,Ariane Fischer,Jana Burchfield,Henrik Fox,Carmen Doebele,Kisho Ohtani,Emmanouil Chavakis,Michael Potente,Marc Tjwa,Carmen Urbich,Andreas M. Zeiher,Stefanie Dimmeler +15 more
TL;DR: It is shown that themiR-17~92 cluster is highly expressed in human endothelial cells and that miR-92a, a component of this cluster, controls the growth of new blood vessels (angiogenesis) and may serve as a valuable therapeutic target in the setting of ischemic disease.
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Cytochrome P450 2C is an EDHF synthase in coronary arteries
Beate Fisslthaler,Rüdiger Popp,Ladislau Kiss,Michael Potente,David R. Harder,Ingrid Fleming,Rudi Busse +6 more
TL;DR: It is shown that the induction of cytochrome P450 (CYP) 2C8/34 in native porcine coronary artery endothelial cells by β-naphthoflavone enhances the formation of 11,12-epoxyeicosatrienoic acid, as well as EDHF-mediated hyperpolarization and relaxation.
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MicroRNA-34a regulates cardiac ageing and function
Reinier A. Boon,Kazuma Iekushi,Stefanie Lechner,Timon Seeger,Ariane Fischer,Susanne Heydt,David Kaluza,Karine Tréguer,Guillaume Carmona,Angelika Bonauer,Anton J.G. Horrevoets,Nathalie Didier,Zenawit Girmatsion,Peter Biliczki,Joachim R. Ehrlich,Hugo A. Katus,Oliver Müller,Michael Potente,Michael Potente,Andreas M. Zeiher,Heiko Hermeking,Stefanie Dimmeler +21 more
TL;DR: Age-induced expression of miR-34a and inhibition of its target PNUTS is identified as a key mechanism that regulates cardiac contractile function during ageing and after acute myocardial infarction, by inducing DNA damage responses and telomere attrition.
Journal ArticleDOI
Endothelial adherens junctions control tight junctions by VE-cadherin-mediated upregulation of claudin-5.
Andrea Taddei,Costanza Giampietro,Annarita Conti,Fabrizio Orsenigo,Ferruccio Breviario,Valentina Pirazzoli,Michael Potente,Christopher Daly,Stefanie Dimmeler,Elisabetta Dejana,Elisabetta Dejana +10 more
TL;DR: It is shown that endothelial VE-cadherin at AJs upregulates the gene encoding the TJ adhesive protein claudin-5, and this effect requires the release of the inhibitory activity of forkhead box factor FoxO1 and the Tcf-4–β-catenin transcriptional repressor complex.