M
Michael R. Wilson
Researcher at University of California, San Francisco
Publications - 213
Citations - 10183
Michael R. Wilson is an academic researcher from University of California, San Francisco. The author has contributed to research in topics: Medicine & Antibody. The author has an hindex of 38, co-authored 168 publications receiving 6682 citations. Previous affiliations of Michael R. Wilson include Boston University & University of Toronto.
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Journal ArticleDOI
The let-7 MicroRNA represses cell proliferation pathways in human cells
Charles D. Johnson,Aurora Esquela-Kerscher,Giovanni Stefani,Mike Byrom,Kevin Kelnar,Dmitriy Ovcharenko,Michael R. Wilson,Xiaowei Wang,Jeffrey Shelton,Jaclyn Shingara,Lena Chin,David F.M. Brown,Frank J. Slack +12 more
TL;DR: This work reveals the let-7 microRNA to be a master regulator of cell proliferation pathways and shows that multiple genes involved in cell cycle and cell division functions are also directly or indirectly repressed byLet-7.
Journal ArticleDOI
Case Definitions, Diagnostic Algorithms, and Priorities in Encephalitis: Consensus Statement of the International Encephalitis Consortium
Arun Venkatesan,Allan R. Tunkel,Karen C. Bloch,Adam S. Lauring,James J. Sejvar,Ari Bitnun,Jean-Paul Stahl,Alexandra Mailles,M. Drebot,Charles E. Rupprecht,Jonathan S. Yoder,Jennifer R. Cope,Michael R. Wilson,Richard J. Whitley,John S. Sullivan,Julia Granerod,Cheryl A Jones,Keith Eastwood,Katherine N. Ward,Katherine N. Ward,David N Durrheim,M. V. Solbrig,L. Guo-Dong,Carol A. Glaser,Heather Sheriff,David W. Brown,Eileen C. Farnon,Sharon Messenger,Beverley J. Paterson,Ariane Soldatos,Sharon L. Roy,Govinda S. Visvesvara,Michael L. Beach,Roger S. Nasci,Carol Pertowski,Scott Schmid,Lisa Rascoe,Joel M. Montgomery,Suxiang Tong,Robert F. Breiman,Richard Franka,Matt Keuhnert,Fred Angulo,James D. Cherry +43 more
TL;DR: A consensus document is presented that proposes a standardized case definition and diagnostic guidelines for evaluation of adults and children with suspected encephalitis and will serve as a practical aid to clinicians evaluating patients with suspectedEncephalitis.
Journal ArticleDOI
Actionable Diagnosis of Neuroleptospirosis by Next-Generation Sequencing
Michael R. Wilson,Samia N. Naccache,Erik Samayoa,Mark Biagtan,Hiba Bashir,Guixia Yu,Shahriar M. Salamat,Sneha Somasekar,Scot Federman,Steve Miller,Robert A. Sokolic,Elizabeth Garabedian,Fabio Candotti,Rebecca H. Buckley,Kurt D. Reed,Teresa L. Meyer,Christine M. Seroogy,Renee Galloway,Sheryl L Henderson,James E. Gern,Joseph L. DeRisi,Charles Y. Chiu +21 more
TL;DR: A 14-year-old boy with severe combined immunodeficiency presented three times to a medical facility over a period of 4 months with fever and headache that progressed to hydrocephalus and status epilepticus necessitating a medically induced coma, confirming evidence of Leptospira santarosai infection.
Journal ArticleDOI
Clinical Metagenomic Sequencing for Diagnosis of Meningitis and Encephalitis
Michael R. Wilson,Hannah A. Sample,Kelsey C. Zorn,Shaun Arevalo,Guixia Yu,John Neuhaus,Scot Federman,Doug Stryke,Benjamin Briggs,Charles Langelier,Amy C. Berger,Vanja C. Douglas,S. Andrew Josephson,Felicia C. Chow,Brent D. Fulton,Joseph L. DeRisi,Jeffrey M. Gelfand,Samia N. Naccache,Jeffrey M. Bender,Jennifer Dien Bard,Jamie A. Murkey,Magrit Carlson,Paul M. Vespa,Tara Vijayan,Paul R Allyn,Shelley Campeau,Romney M. Humphries,Jeffrey D. Klausner,Czarina Ganzon,Fatemeh Memar,Nicolle Anne Ocampo,Lara Zimmermann,Stuart H. Cohen,Christopher R. Polage,Roberta L. DeBiasi,Barbara Haller,Ronald H. Dallas,Gabriela Maron,Randall T. Hayden,Kevin Messacar,Samuel R. Dominguez,Steve Miller,Charles Y. Chiu +42 more
TL;DR: Routine microbiologic testing is often insufficient to detect all neuroinvasive pathogens, so metagenomic NGS of CSF obtained from patients with meningitis or encephalitis improved diagnosis of neurologic infections and provided actionable information in some cases.
Journal ArticleDOI
Rapid pathogen detection by metagenomic next-generation sequencing of infected body fluids.
Wei Gu,Xianding Deng,Marco Lee,Yasemin D. Sucu,Shaun Arevalo,Doug Stryke,Scot Federman,Allan Gopez,Kevin Reyes,Kelsey C. Zorn,Hannah A. Sample,Guixia Yu,Gurpreet Ishpuniani,Benjamin Briggs,Eric D. Chow,Amy C. Berger,Michael R. Wilson,Candace Wang,Elaine Hsu,Steve Miller,Joseph L. DeRisi,Charles Y. Chiu +21 more
TL;DR: A universal method enables high-specificity, unbiased pathogen detection from diverse body fluids using metagenomic sequencing and may accelerate clinical decisions.