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Michael Snyder

Researcher at Stanford University

Publications -  938
Citations -  150929

Michael Snyder is an academic researcher from Stanford University. The author has contributed to research in topics: Gene & Genome. The author has an hindex of 169, co-authored 840 publications receiving 130225 citations. Previous affiliations of Michael Snyder include Wyss Institute for Biologically Inspired Engineering & Public Health Research Institute.

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RNA-Seq: a revolutionary tool for transcriptomics

TL;DR: The RNA-Seq approach to transcriptome profiling that uses deep-sequencing technologies provides a far more precise measurement of levels of transcripts and their isoforms than other methods.
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Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project

Ewan Birney, +320 more
- 14 Jun 2007 - 
TL;DR: Functional data from multiple, diverse experiments performed on a targeted 1% of the human genome as part of the pilot phase of the ENCODE Project are reported, providing convincing evidence that the genome is pervasively transcribed, such that the majority of its bases can be found in primary transcripts.
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Functional profiling of the Saccharomyces cerevisiae genome.

Guri Giaever, +72 more
- 25 Jul 2002 - 
TL;DR: It is shown that previously known and new genes are necessary for optimal growth under six well-studied conditions: high salt, sorbitol, galactose, pH 8, minimal medium and nystatin treatment, and less than 7% of genes that exhibit a significant increase in messenger RNA expression are also required for optimal Growth in four of the tested conditions.
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Functional Characterization of the S. cerevisiae Genome by Gene Deletion and Parallel Analysis

TL;DR: A total of 6925 Saccharomyces cerevisiae strains were constructed, by a high-throughput strategy, each with a precise deletion of one of 2026 ORFs (more than one-third of the ORFs in the genome), finding that 17 percent were essential for viability in rich medium.

An integrated encyclopedia of DNA elements in the human genome

Ian Dunham, +442 more
TL;DR: The Encyclopedia of DNA Elements project provides new insights into the organization and regulation of the authors' genes and genome, and is an expansive resource of functional annotations for biomedical research.