Michael Snyder

TL;DR: It is found that septins are multifunctional proteins with specific domains involved in distinct molecular interactions required for assembly, localization, and function within the cell.

TL;DR: Using statistically aided, long-read haplotyping (SLRH), a rapid, accurate method that uses a statistical algorithm to take advantage of the partially phased information contained in long genomic fragments analyzed by short-read sequencing, this work phases 99% of single-nucleotide variants in three human genomes into long haplotype blocks 0.2–1 Mbp in length.

TL;DR: The extent of physiological protein transcytosis to the healthy brain is revealed, a mechanism of widespread BBB dysfunction with age and a strategy for enhanced drug delivery is revealed.

TL;DR: An extensive study analysing a broad spectrum of RNA-seq workflows and proposing a comprehensive analysis protocol, named RNACocktail, along with a computational pipeline achieving high accuracy, which could help researchers extract more biologically relevant predictions by broad analysis of the transcriptome.

TL;DR: Most of a 9 kb region of the Drosophila genome containing genes for several cuticle proteins has been sequenced and five cuticle-gene-like sequences have been identified and mapped, and they are discussed as a model small gene family.