M
Michael Snyder
Researcher at Stanford University
Publications - 938
Citations - 150929
Michael Snyder is an academic researcher from Stanford University. The author has contributed to research in topics: Gene & Genome. The author has an hindex of 169, co-authored 840 publications receiving 130225 citations. Previous affiliations of Michael Snyder include Wyss Institute for Biologically Inspired Engineering & Public Health Research Institute.
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Journal ArticleDOI
DNA replication-timing analysis of human chromosome 22 at high resolution and different developmental states
Eric J. White,Olof Emanuelsson,David Scalzo,Thomas Royce,Steven T. Kosak,Edward J. Oakeley,Sherman M. Weissman,Mark Gerstein,Mark Groudine,Mark Groudine,Michael Snyder,Dirk Schübeler +11 more
TL;DR: The results suggest that novel transcribed regions with low coding potential exhibit a strong propensity for early DNA replication, and their activity is linked to the replication-timing program.
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Personal genome sequencing: current approaches and challenges
TL;DR: The current state of personal genome sequencing, the main steps involved in determining a genome sequence, the challenges and performance metrics for evaluating the accuracy of the reconstruction, and the possible individual and societal benefits are discussed.
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Impact of Chromatin Structures on DNA Processing for Genomic Analyses
Leonid Teytelman,Bilge Özaydın,Oliver A. Zill,Philippe Lefrançois,Michael Snyder,Jasper Rine,Michael B. Eisen +6 more
TL;DR: It is reported that chromatin structure also affects laboratory DNA manipulation in ways that distort the results of chromatin immunoprecipitation experiments, and the pervasiveness of this bias genome-wide is established and it is suggested that this bias can be used to detect differences in chromatin structures across the genome.
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Whole-exome sequencing identifies tetratricopeptide repeat domain 7A (TTC7A) mutations for combined immunodeficiency with intestinal atresias
Rui Chen,Silvia Giliani,Gaetana Lanzi,George I. Mias,Silvia Lonardi,Kerry Dobbs,John P. Manis,Hogune Im,Jennifer E. G. Gallagher,Douglas H. Phanstiel,Ghia Euskirchen,Philippe Lacroute,Keith Bettinger,Daniele Moratto,Katja G. Weinacht,Davide Montin,Eleonora Gallo,Giovanna Mangili,Fulvio Porta,Lucia Dora Notarangelo,Stefania Pedretti,Waleed Al-Herz,Wasmi Alfahdli,Anne Marie Comeau,Russell S. Traister,Sung-Yun Pai,Graziella Carella,Fabio Facchetti,Kari C. Nadeau,Michael Snyder,Luigi D. Notarangelo,Luigi D. Notarangelo +31 more
TL;DR: The results strongly suggest that TTC7A gene defects cause CID-MIA.
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Dynamic trans-acting factor colocalization in human cells.
TL;DR: In this article, a large-scale mass spectrometry analysis of immunoprecipitations of 50 transacting factors (TFs) was performed to analyze TF colocalization within a cell type and across multiple cell lines at an unprecedented level.