M
Michael T. McMahon
Researcher at Johns Hopkins University School of Medicine
Publications - 148
Citations - 7820
Michael T. McMahon is an academic researcher from Johns Hopkins University School of Medicine. The author has contributed to research in topics: Magnetic resonance imaging & Reporter gene. The author has an hindex of 46, co-authored 136 publications receiving 6803 citations. Previous affiliations of Michael T. McMahon include University of California, Berkeley & Massachusetts Institute of Technology.
Papers
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Journal ArticleDOI
High-resolution molecular structure of a peptide in an amyloid fibril determined by magic angle spinning NMR spectroscopy
Christopher P. Jaroniec,Cait E. MacPhee,Vikram S. Bajaj,Michael T. McMahon,Christopher M. Dobson,Robert G. Griffin +5 more
TL;DR: The results indicate that TTR(105-115) adopts an extended beta-strand conformation in the amyloid fibrils such that both the main- and side-chain torsion angles are close to their optimal values.
Journal ArticleDOI
Mesoporous silica-coated hollow manganese oxide nanoparticles as positive T1 contrast agents for labeling and MRI tracking of adipose-derived mesenchymal stem cells.
Taeho Kim,Eric N. Momin,Jonghoon Choi,Kristy Yuan,Hasan A. Zaidi,Jaeyun Kim,Mihyun Park,Nohyun Lee,Michael T. McMahon,Michael T. McMahon,Alfredo Quiñones-Hinojosa,Jeff W.M. Bulte,Taeghwan Hyeon,Assaf A. Gilad,Assaf A. Gilad +14 more
TL;DR: These novel nanoparticles may extend the arsenal of currently available nanoparticle MR contrast agents by providing positive contrast on T1-weighted images at high magnetic field strengths by enabling optimal access of water molecules to the magnetic core.
Journal ArticleDOI
Artificial reporter gene providing MRI contrast based on proton exchange
Assaf A. Gilad,Michael T. McMahon,Piotr Walczak,Paul T. Winnard,Venu Raman,Hanneke W. M. van Laarhoven,Hanneke W. M. van Laarhoven,Cynthia M Skoglund,Jeff W.M. Bulte,Peter C.M. van Zijl +9 more
TL;DR: A nonmetallic, biodegradable, lysine rich–protein (LRP) reporter, the prototype of a potential family of genetically engineered reporters expressing artificial proteins with frequency-selective contrast, which can be switched on and off.
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Quantifying Exchange Rates in Chemical Exchange Saturation Transfer Agents Using the Saturation Time and Saturation Power Dependencies of the Magnetization Transfer Effect on the Magnetic Resonance Imaging Signal (QUEST and QUESP): pH Calibration for Poly-l-Lysine and a Starburst Dendrimer
Michael T. McMahon,Assaf A. Gilad,Jinyuan Zhou,Jinyuan Zhou,Phillip Zhe Sun,Phillip Zhe Sun,Jeff W.M. Bulte,Peter C.M. van Zijl,Peter C.M. van Zijl +8 more
TL;DR: The ability to measure proton exchange rates in tissue using MRI would be very useful for quantitative assessment of magnetization transfer properties, both in conventional MT imaging and in the more recent chemical exchange saturation transfer (CEST) approach.
Journal ArticleDOI
Natural D-glucose as a biodegradable MRI contrast agent for detecting cancer.
Kannie W. Y. Chan,Michael T. McMahon,Michael T. McMahon,Yoshinori Kato,Yoshinori Kato,Guanshu Liu,Guanshu Liu,Jeff W.M. Bulte,Zaver M. Bhujwalla,Zaver M. Bhujwalla,Dmitri Artemov,Dmitri Artemov,Peter C.M. van Zijl,Peter C.M. van Zijl +13 more
TL;DR: The goal was to explore the possibility of using simple D‐glucose as an infusable biodegradable MRI agent for cancer detection.