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Michel Monsigny

Researcher at University of Orléans

Publications -  253
Citations -  11134

Michel Monsigny is an academic researcher from University of Orléans. The author has contributed to research in topics: Lectin & Transfection. The author has an hindex of 51, co-authored 252 publications receiving 10876 citations. Previous affiliations of Michel Monsigny include Centre national de la recherche scientifique & Parfums Christian Dior.

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Efficient Gene Transfer by Histidylated Polylysine/pDNA Complexes

TL;DR: A cationic polymer is designed that forms complexes with a plasmid DNA (pDNA) and mediates the transfection of various cell lines in the absence of chloroquine or fusogenic peptides and was optimal with a polylysine having 38 +/- 5% of the epsilon-amino groups substituted with histidyl residues.
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Sugar-Lectin Interactions: How Does Wheat-Germ Agglutinin Bind Sialoglycoconjugates?

TL;DR: The specific binding of N- acetylneuraminic acid to wheat-germ agglutinin is based on configuration similarities between N-acetylneursic acid and N- facetedglucosamine and an adjacent hydroxyl group, both in an equatorial position are shown to be the main determinants.
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Colorimetric determination of neutral sugars by a resorcinol sulfuric acid micromethod

TL;DR: A microscale colorimetric assay for neutral sugars, in which neutral sugars react with resorcinol in the presence of 75% sulfuric acid solution is described, which allows accurate determinations with small samples containing 1 to 100 nmol of neutral sugars and is quite convenient for detection of glycoconjugates in chromatographic column effluents.