M
Mikael Rørdam Andersen
Researcher at Technical University of Denmark
Publications - 112
Citations - 7716
Mikael Rørdam Andersen is an academic researcher from Technical University of Denmark. The author has contributed to research in topics: Chinese hamster ovary cell & Gene. The author has an hindex of 38, co-authored 111 publications receiving 6577 citations. Previous affiliations of Mikael Rørdam Andersen include Novo Nordisk Foundation & University of Maryland, Baltimore.
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Journal ArticleDOI
Genome sequencing and analysis of the versatile cell factory Aspergillus niger CBS 513.88
Herman Jan Pel,Johannes H. de Winde,Johannes H. de Winde,David B. Archer,Paul S. Dyer,Gerald Hofmann,Peter J. Schaap,Geoffrey Turner,Ronald P. de Vries,Richard Albang,Kaj Albermann,Mikael Rørdam Andersen,Jannick Dyrløv Bendtsen,Jacques A.E. Benen,Marco A. van den Berg,Stefaan Breestraat,Mark X. Caddick,Roland Contreras,Michael Cornell,Pedro M. Coutinho,Etienne Danchin,Alfons J. M. Debets,Peter J. T. Dekker,Piet W.M. van Dijck,Alard Van Dijk,Lubbert Dijkhuizen,Arnold J. M. Driessen,Christophe d'Enfert,Steven Geysens,Coenie Goosen,Gert S.P. Groot,Piet W. J. de Groot,Thomas Guillemette,Bernard Henrissat,Marga Herweijer,Johannes Petrus Theodorus Wilhelmus Van Den Hombergh,Cees A. M. J. J. van den Hondel,René T. J. M. van der Heijden,Rachel M. van der Kaaij,Frans M. Klis,Harrie J. Kools,Christian P. Kubicek,Patricia Ann van Kuyk,Jürgen Lauber,Xin Lu,Marc J. E. C. van der Maarel,Rogier Meulenberg,Hildegard Henna Menke,Martin Mortimer,Jens Nielsen,Stephen G. Oliver,Maurien M.A. Olsthoorn,K. Pal,K. Pal,Noël Nicolaas Maria Elisabeth Van Peij,Arthur F. J. Ram,Ursula Rinas,Johannes Andries Roubos,Cornelis Maria Jacobus Sagt,Monika Schmoll,Jibin Sun,David W. Ussery,János Varga,Wouter Vervecken,Peter J.J. Van De Vondervoort,Holger Wedler,Han A. B. Wösten,An-Ping Zeng,Albert J. J. van Ooyen,Jaap Visser,Hein Stam +70 more
TL;DR: The filamentous fungus Aspergillus niger is widely exploited by the fermentation industry for the production of enzymes and organic acids, particularly citric acid, and the sequenced genome revealed a large number of major facilitator superfamily transporters and fungal zinc binuclear cluster transcription factors.
Journal ArticleDOI
The genomic sequence of the Chinese hamster ovary (CHO)-K1 cell line
Xun Xu,Harish Nagarajan,Nathan E. Lewis,Shengkai Pan,Zhiming Cai,Xin Liu,Wenbin Chen,Min Xie,Wenliang Wang,Stephanie Hammond,Mikael Rørdam Andersen,Norma F. Neff,Benedetto Passarelli,Winston Koh,H. Christina Fan,Jianbin Wang,Yaoting Gui,Kelvin H. Lee,Michael J. Betenbaugh,Michael J. Betenbaugh,Stephen R. Quake,Iman Famili,Bernhard O. Palsson,Jun Wang +23 more
TL;DR: A draft genomic sequence of the CHO-K1 ancestral cell line is presented and it is discussed how the availability of this genome sequence may facilitate genome-scale science for the optimization of biopharmaceutical protein production.
Journal ArticleDOI
Comparative genomics reveals high biological diversity and specific adaptations in the industrially and medically important fungal genus Aspergillus
Ronald P. de Vries,Robert Riley,Ad Wiebenga,Guillermo Aguilar-Osorio,Sotiris Amillis,Cristiane Uchima,Gregor Anderluh,Mojtaba Asadollahi,Marion Askin,Marion Askin,Kerrie Barry,Evy Battaglia,Özgür Bayram,Özgür Bayram,Tiziano Benocci,Susanna A. Braus-Stromeyer,Camila Caldana,David Cánovas,David Cánovas,Gustavo C. Cerqueira,Fusheng Chen,Wanping Chen,Cindy Choi,Alicia Clum,Renato Augusto Corrêa dos Santos,André Damasio,George Diallinas,Tamás Emri,Erzsébet Fekete,Michel Flipphi,Susanne Freyberg,Antonia Gallo,Christos Gournas,Rob Habgood,Matthieu Hainaut,María Harispe,Bernard Henrissat,Bernard Henrissat,Bernard Henrissat,Kristiina Hildén,Ryan Hope,Abeer Hossain,Eugenia Karabika,Eugenia Karabika,Levente Karaffa,Zsolt Karányi,Nada Kraševec,Alan Kuo,Harald Kusch,Kurt LaButti,Ellen Lagendijk,Alla Lapidus,Alla Lapidus,Anthony Levasseur,Erika Lindquist,Anna Lipzen,Antonio F. Logrieco,Andrew MacCabe,Miia R. Mäkelä,Iran Malavazi,Petter Melin,Vera Meyer,Natalia Mielnichuk,Natalia Mielnichuk,Márton Miskei,Ákos Molnár,Giuseppina Mulè,Chew Yee Ngan,Margarita Orejas,Erzsébet Orosz,Erzsébet Orosz,Jean Paul Ouedraogo,Jean Paul Ouedraogo,Karin M. Overkamp,Hee-Soo Park,Giancarlo Perrone,François Piumi,François Piumi,Peter J. Punt,Arthur F. J. Ram,Ana Ramón,Stefan Rauscher,Eric Record,Diego Mauricio Riaño-Pachón,Vincent Robert,Julian Röhrig,Roberto Ruller,Asaf Salamov,Nadhira Salih,Nadhira Salih,Rob Samson,Erzsébet Sándor,Manuel Sanguinetti,Tabea Schütze,Tabea Schütze,Kristina Sepčić,Ekaterina Shelest,Gavin Sherlock,Vicky Sophianopoulou,Fabio M. Squina,Hui Sun,Antonia Susca,Richard B. Todd,Adrian Tsang,Shiela E. Unkles,Nathalie van de Wiele,Diana van Rossen-Uffink,Juliana Velasco de Castro Oliveira,Tammi Camilla Vesth,Jaap Visser,Jae-Hyuk Yu,Miaomiao Zhou,Mikael Rørdam Andersen,David B. Archer,Scott E. Baker,Isabelle Benoit,Isabelle Benoit,Axel A. Brakhage,Gerhard H. Braus,Reinhard Fischer,Jens Christian Frisvad,Gustavo H. Goldman,Jos Houbraken,Berl R. Oakley,István Pócsi,Claudio Scazzocchio,Claudio Scazzocchio,Bernhard Seiboth,Patricia A. vanKuyk,Patricia A. vanKuyk,Jennifer R. Wortman,Paul S. Dyer,Igor V. Grigoriev +132 more
TL;DR: In this article, a comparative genomics and experimental study of the aspergilli genus is presented, which allows for the first time a genus-wide view of the biological diversity of the Aspergillus and in many, but not all, cases linked genome differences to phenotype.
Journal ArticleDOI
Comparative genomics of citric-acid-producing Aspergillus niger ATCC 1015 versus enzyme-producing CBS 513.88
Mikael Rørdam Andersen,Margarita Salazar,Peter J. Schaap,Peter J. I. van de Vondervoort,David E. Culley,Jette Thykaer,Jens Christian Frisvad,Kristian Fog Nielsen,Richard Albang,Kaj Albermann,Randy M. Berka,Gerhard H. Braus,Susanna A. Braus-Stromeyer,Luis M. Corrochano,Ziyu Dai,Piet W.M. van Dijck,Gerald Hofmann,Linda L. Lasure,Jon K. Magnuson,Hildegard Henna Menke,M. Meijer,Susan Lisette Meijer,Jakob Blæsbjerg Nielsen,Michael Lynge Nielsen,Albert J. J. van Ooyen,Herman Jan Pel,Lars Kongsbak Poulsen,Rob Samson,Hein Stam,Adrian Tsang,Johannes Maarten Van Den Brink,Alex Atkins,Andrea Aerts,Harris Shapiro,Jasmyn Pangilinan,Asaf Salamov,Yigong Lou,Erika Lindquist,Susan Lucas,Jane Grimwood,Igor V. Grigoriev,Christian P. Kubicek,Diego Martinez,Noël Nicolaas Maria Elisabeth Van Peij,Johannes Andries Roubos,Jens Nielsen,Scott E. Baker +46 more
TL;DR: In this article, the authors performed whole-genome sequencing of the Aspergillus niger wild-type strain (ATCC 1015) and produced a genome sequence of very high quality.
Comparative genomics of citric-acid producing Aspergillus niger ATCC 1015 versus enzyme-producing CBS 513.88 [working title: Aspergillus niger strain evolution]
Susan Lucas,Igor V. Grigoriev,Harris Shapiro,Andrea Aerts,Alex Atkins,Asaf Salamov,Erika Lindquist,Jasmyn Pangilinan,Yunian Lou,Jane Grimwood,Mikael Rørdam Andersen,Margarita Salazar,Peter J. Schaap,P de Vondervoot,David E. Culley,Scott E. Baker,Jette Thykaer,Jens Christian Frisvad,Kristian Fog Nielsen,Richard Albang,Kaj Albermann,Randy M. Berka,Gerhard H. Braus,Susanna A. Braus-Stromeyer,Luis M. Corrochano,Ziyu Dai,P van Dijck,Gerald Hofmann,Linda L. Lasure,J Magnusson,Susan Lisette Meijer,Jens Nielsen,Michael Lynge Nielsen,A van Ooyen,K Panther,Herman Jan Pel,Lars Kongsbak Poulsen,Rob Samson,Hein Stam,Adrian Tsang,J den Brink,Christian P. Kubicek,Diego Martinez,N van Peij,Johannes Andries Roubos +44 more
TL;DR: In this paper, the authors performed whole-genome sequencing of the Aspergillus niger wild-type strain (ATCC 1015) and produced a genome sequence of very high quality.