Mikkel-Holger S. Sinding

TL;DR: The observations suggest that the BGISEQ-500 holds the potential to represent a valid and potentially valuable alternative platform for palaeogenomic data generation that is worthy of future exploration by those interested in the sequencing and analysis of degraded DNA.

TL;DR: The densely sampled alignment provides a single-base-pair map of selection, has more than doubled the fraction of bases that are confidently predicted to be under conservation and reveals extensive patterns of weak selection in predominantly non-coding DNA.

TL;DR: Four Illumina library preparation protocols are compared, including two “single‐tube” methods developed for this study with the explicit aim of improving data quality and reducing preparation time and expenses, and single‐tube protocols increase library complexity, yield more reads that map uniquely to the reference genome, reduce processing time, and may decrease laboratory costs by 90%.

TL;DR: This assessment made use of risk quotient calculations to summarize the cumulative effects of different OHC classes and mercury for which critical body burdens can be estimated for wildlife across the Arctic.

TL;DR: The analysis indicates that American dogs were not derived from North American wolves but likely originated from a Siberian ancestor, and form a monophyletic lineage that likely originated in Siberia and dispersed into the Americas alongside people.