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Miles A. Whittington

Researcher at Hull York Medical School

Publications -  216
Citations -  23413

Miles A. Whittington is an academic researcher from Hull York Medical School. The author has contributed to research in topics: Population & Hippocampal formation. The author has an hindex of 77, co-authored 212 publications receiving 21961 citations. Previous affiliations of Miles A. Whittington include University of Bristol & University of Leeds.

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Synchronized oscillations in interneuron networks driven by metabotropic glutamate receptor activation

TL;DR: It is proposed that interneuron network oscillations, in conjunction with intrinsic membrane resonances and long-loop (such as thalamocortical) interactions, contribute to 40-Hz rhythms in vivo.
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Gamma rhythms and beta rhythms have different synchronization properties.

TL;DR: A simplified model is used to show that the different rhythms in the CA1 region of the hippocampus employ different dynamical mechanisms to synchronize, based on different ionic currents, which are consistent with data suggesting that gamma rhythms are used for relatively local computations whereas beta rhythms are use for higher level interactions involving more distant structures.
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Inhibition-based rhythms: experimental and mathematical observations on network dynamics

TL;DR: This review will provide the reader with a brief outline of the basic properties of inhibition-based oscillations in the CNS by combining research from laboratory models, large-scale neuronal network simulations, and mathematical analysis.
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Prion protein is necessary for normal synaptic function

TL;DR: It is argued that loss of function of PrPc may contribute to the early synaptic loss3 and neuronal degeneration seen in Creutzfeldt–Jakob disease and scrapie and bovine spongiform encephalopathy in animals.