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Min Li

Researcher at University of Oklahoma Health Sciences Center

Publications -  505
Citations -  16372

Min Li is an academic researcher from University of Oklahoma Health Sciences Center. The author has contributed to research in topics: Medicine & Pancreatic cancer. The author has an hindex of 59, co-authored 310 publications receiving 12877 citations. Previous affiliations of Min Li include Chinese Academy of Sciences & University of Oklahoma.

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Microenvironment-induced PTEN loss by exosomal microRNA primes brain metastasis outgrowth

TL;DR: A remarkable plasticity of PTEN expression in metastatic tumour cells in response to different organ microenvironments is demonstrated, underpinning an essential role of co-evolution between the metastatic cells and their microenvironment during the adaptive metastatic outgrowth.
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Three-Dimensional Structure of Human Monoamine Oxidase a (Mao A): Relation to the Structures of Rat Mao a and Human Mao B

TL;DR: Data support the proposal that hMAO A involves a change from the dimeric to the monomeric form through a Glu-151 --> Lys mutation that is specific of hMAo A and put into question the use of MAO A from nonhuman sources in drug development for use in humans.
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Insights into the mode of inhibition of human mitochondrial monoamine oxidase B from high-resolution crystal structures.

TL;DR: The 1.7-Å structure of the reversible isatin–MAO-B complex has been determined; it forms a basis for the interpretation of the enzyme's structure when bound to either reversible or irreversible inhibitors.
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CFIm25 links alternative polyadenylation to glioblastoma tumour suppression

TL;DR: CFIm25 is identified as a broad repressor of proximal poly(A) site usage that, when depleted, increases cell proliferation and is revealed as a previously unknown connection between CFIm25 and glioblastoma tumorigenicity.
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Profiling of 95 MicroRNAs in Pancreatic Cancer Cell Lines and Surgical Specimens by Real-Time PCR Analysis

TL;DR: Pancreatic cancer tissues or cell lines have a unique miRNA profiling pattern at the individual basis compared with relatively normal pancreatic tissues or cells as well as chronic pancreatitis tissue, indicating the individual diversity of pancreatic cancer.