Author
Minah Park
Other affiliations: University of Hong Kong
Bio: Minah Park is an academic researcher from Li Ka Shing Faculty of Medicine, University of Hong Kong. The author has contributed to research in topics: Medicine & Confidence interval. The author has an hindex of 6, co-authored 6 publications receiving 1481 citations. Previous affiliations of Minah Park include University of Hong Kong.
Papers
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Centers for Disease Control and Prevention1, Emory University2, University of New South Wales3, Pan American Health Organization4, National Health Laboratory Service5, University of Oslo6, Norwegian Institute of Public Health7, Li Ka Shing Faculty of Medicine, University of Hong Kong8, Singapore Ministry of Health9, Medical University of Vienna10, Chinese Center for Disease Control and Prevention11, Statens Serum Institut12, All India Institute of Medical Sciences13, Thailand Ministry of Public Health14, Robert Koch Institute15
TL;DR: These global influenza-associated respiratory mortality estimates are higher than previously reported, suggesting that previous estimates might have underestimated disease burden.
1,658 citations
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TL;DR: South Korea is experiencing the largest outbreak of Middle East respiratory syndrome coronavirus infections outside the Arabian Peninsula, with 166 laboratory-confirmed cases, including 24 deaths up to 19 June 2015, and it is unlikely that infectiousness precedes symptom onset.
Abstract: South Korea is experiencing the largest outbreak of Middle East respiratory syndrome coronavirus infections outside the Arabian Peninsula, with 166 laboratory-confirmed cases, including 24 deaths up to 19 June 2015. We estimated that the mean incubation period was 6.7 days and the mean serial interval 12.6 days. We found it unlikely that infectiousness precedes symptom onset. Based on currently available data, we predict an overall case fatality risk of 21% (95% credible interval: 14–31).
294 citations
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TL;DR: Variation in the incubation period distribution of MERS coronavirus infection for cases in South Korea and in Saudi Arabia could be associated with differences in ascertainment or reporting of exposure dates and illness onset dates, differences in the source or mode of infection, or environmental differences.
Abstract: The incubation period is an important epidemiologic distribution, it is often incorporated in case definitions, used to determine appropriate quarantine periods, and is an input to mathematical modeling studies. Middle East Respiratory Syndrome coronavirus (MERS) is an emerging infectious disease in the Arabian Peninsula. There was a large outbreak of MERS in South Korea in 2015. We examined the incubation period distribution of MERS coronavirus infection for cases in South Korea and in Saudi Arabia. Using parametric and nonparametric methods, we estimated a mean incubation period of 6.9 days (95% credibility interval: 6.3–7.5) for cases in South Korea and 5.0 days (95% credibility interval: 4.0–6.6) among cases in Saudi Arabia. In a log-linear regression model, the mean incubation period was 1.42 times longer (95% credibility interval: 1.18–1.71) among cases in South Korea compared to Saudi Arabia. The variation that we identified in the incubation period distribution between locations could be associated with differences in ascertainment or reporting of exposure dates and illness onset dates, differences in the source or mode of infection, or environmental differences.
63 citations
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TL;DR: A longer incubation period was associated with a reduction in the risk for death and a higher likelihood of survival in patients who had laboratory-confirmed infection with Middle East respiratory syndrome coronavirus.
Abstract: We analyzed data for 170 patients in South Korea who had laboratory-confirmed infection with Middle East respiratory syndrome coronavirus. A longer incubation period was associated with a reduction in the risk for death (adjusted odds ratio/1-day increase in incubation period 0.83, 95% credibility interval 0.68-1.03).
46 citations
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TL;DR: The impact of influenza on mortality in Korea is substantial, particularly among the elderly and the rural population, and more-comprehensive studies may be needed to estimate the full impact of flu.
44 citations
Cited by
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TL;DR: The results support current proposals for the length of quarantine or active monitoring of persons potentially exposed to SARS-CoV-2, although longer monitoring periods might be justified in extreme cases.
Abstract: Using news reports and press releases from provinces, regions, and countries outside Wuhan, Hubei province, China, this analysis estimates the length of the incubation period of COVID-19 and its pu...
5,215 citations
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Gregory A. Roth1, Gregory A. Roth2, Degu Abate3, Kalkidan Hassen Abate4 +1025 more•Institutions (333)
TL;DR: Non-communicable diseases comprised the greatest fraction of deaths, contributing to 73·4% (95% uncertainty interval [UI] 72·5–74·1) of total deaths in 2017, while communicable, maternal, neonatal, and nutritional causes accounted for 18·6% (17·9–19·6), and injuries 8·0% (7·7–8·2).
5,211 citations
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TL;DR: It is inferred that epidemics are already growing exponentially in multiple major cities of China with a lag time behind the Wuhan outbreak of about 1–2 weeks, and that other major Chinese cities are probably sustaining localised outbreaks.
3,938 citations
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TL;DR: The emergence of Middle East respiratory syndrome coronavirus (MERS-CoV) in 2012 marked the second introduction of a highly pathogenic coronav virus into the human population in the twenty-first century, and the current state of development of measures to combat emerging coronaviruses is discussed.
Abstract: The emergence of Middle East respiratory syndrome coronavirus (MERS-CoV) in 2012 marked the second introduction of a highly pathogenic coronavirus into the human population in the twenty-first century. The continuing introductions of MERS-CoV from dromedary camels, the subsequent travel-related viral spread, the unprecedented nosocomial outbreaks and the high case-fatality rates highlight the need for prophylactic and therapeutic measures. Scientific advancements since the 2002-2003 severe acute respiratory syndrome coronavirus (SARS-CoV) pandemic allowed for rapid progress in our understanding of the epidemiology and pathogenesis of MERS-CoV and the development of therapeutics. In this Review, we detail our present understanding of the transmission and pathogenesis of SARS-CoV and MERS-CoV, and discuss the current state of development of measures to combat emerging coronaviruses.
2,794 citations
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Centers for Disease Control and Prevention1, Emory University2, University of New South Wales3, Pan American Health Organization4, National Health Laboratory Service5, Norwegian Institute of Public Health6, University of Oslo7, Li Ka Shing Faculty of Medicine, University of Hong Kong8, Singapore Ministry of Health9, Medical University of Vienna10, Chinese Center for Disease Control and Prevention11, Statens Serum Institut12, All India Institute of Medical Sciences13, Thailand Ministry of Public Health14, Robert Koch Institute15
TL;DR: These global influenza-associated respiratory mortality estimates are higher than previously reported, suggesting that previous estimates might have underestimated disease burden.
1,658 citations