M
Minghuan Wang
Researcher at Huazhong University of Science and Technology
Publications - 44
Citations - 6276
Minghuan Wang is an academic researcher from Huazhong University of Science and Technology. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 11, co-authored 22 publications receiving 4118 citations. Previous affiliations of Minghuan Wang include University of Rochester & University of Rochester Medical Center.
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Journal ArticleDOI
A paravascular pathway facilitates CSF flow through the brain parenchyma and the clearance of interstitial solutes, including amyloid β.
Jeffrey J. Iliff,Minghuan Wang,Minghuan Wang,Yonghong Liao,Benjamin A. Plogg,Weiguo Peng,Georg Andreas Gundersen,Helene Benveniste,G. Edward Vates,Rashid Deane,Steven A. Goldman,Erlend A. Nagelhus +11 more
TL;DR: An anatomically distinct clearing system in the brain that serves a lymphatic-like function is described and may have relevance for understanding or treating neurodegenerative diseases that involve the mis-accumulation of soluble proteins, such as amyloid β in Alzheimer's disease.
Journal ArticleDOI
Impairment of paravascular clearance pathways in the aging brain
Benjamin T. Kress,Jeffrey J. Iliff,Jeffrey J. Iliff,Maosheng Xia,Maosheng Xia,Minghuan Wang,Helen S. Wei,Douglas M. Zeppenfeld,Lulu Xie,Hongyi Kang,Qiwu Xu,Jason Liew,Benjamin A. Plog,Fengfei Ding,Fengfei Ding,Rashid Deane +15 more
TL;DR: Evaluating the efficiency of CSF–ISF exchange and interstitial solute clearance is impaired in the aging brain found that bulk flow drainage via the glymphatic system is driven by cerebrovascular pulsation, and is dependent on astroglial water channels that line paravascular CSF pathways.
Journal ArticleDOI
Cerebral Arterial Pulsation Drives Paravascular CSF–Interstitial Fluid Exchange in the Murine Brain
Jeffrey J. Iliff,Minghuan Wang,Minghuan Wang,Douglas M. Zeppenfeld,Douglas M. Zeppenfeld,Arun Venkataraman,Benjamin A. Plog,Yonghong Liao,Rashid Deane +8 more
TL;DR: It is demonstrated that cerebral arterial pulsatility is a key driver of paravascular CSF influx into and through the brain parenchyma, and suggested that changes in arterials pulsatility may contribute to accumulation and deposition of toxic solutes, including amyloid β, in the aging brain.
Journal ArticleDOI
Coronavirus Disease 2019 (COVID-2019) Infection Among Health Care Workers and Implications for Prevention Measures in a Tertiary Hospital in Wuhan, China.
Xiaoquan Lai,Minghuan Wang,Chuan Qin,Li Tan,Lusen Ran,Daiqi Chen,Han Zhang,Ke Shang,Chen Xia,Wang Shaokang,Shabei Xu,Wei Wang +11 more
TL;DR: In this study, most infections among health care workers occurred during the early stage of the COVID-19 outbreak and in low-contagion areas; routine screening may be helpful in identifying asymptomatic carriers.
Journal ArticleDOI
Trends in smoking prevalence and implication for chronic diseases in China: serial national cross-sectional surveys from 2003 to 2013.
Minghuan Wang,Xiang Luo,Shabei Xu,Wenhua Liu,Fengfei Ding,Xiaoxiang Zhang,Liang Wang,Jian Liu,Jianping Hu,Wei Wang +9 more
TL;DR: While a consistently high proportion of Chinese men smoked, the standardised smoking prevalence in women younger than 40 years increased from 1·0% in 2003 to 1·6% in 2013, and the association between smoking and chronic diseases by using multiple logistic regression was identified.