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Mingliang Xia

Bio: Mingliang Xia is an academic researcher from Chinese Academy of Sciences. The author has contributed to research in topics: Wavefront & Adaptive optics. The author has an hindex of 7, co-authored 30 publications receiving 181 citations.

Papers
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Journal ArticleDOI
TL;DR: Using an indoor closed-loop configuration optical system, it is demonstrated that the residual error after open-loop correction could be smaller than 0.08lambda (RMS: root mean square value) if the initial wavefront aberration is below 2.5lambda.
Abstract: Used as a wavefront corrector, a liquid crystal spatial modulator (LC-SLM) has good repeatability and linearity, which are essential for open-loop adaptive optics, and the open-loop optical system can increase the light energy efficiency by a factor of two for the LC-SLM and improve the system bandwidth. In order to test the performance of the LC-SLM in open-loop correction, an indoor closed-loop configuration optical system is constructed on the open-loop control method. With this method, it is demonstrated that the residual error after open-loop correction could be smaller than 0.08lambda (RMS: root mean square value) if the initial wavefront aberration is below 2.5lambda (RMS), and the repeatability error of open-loop correction is smaller than 0.01lambda (RMS).

36 citations

Journal ArticleDOI
Mingliang Xia1, Chao Li1, Lifa Hu1, Zhaoliang Cao1, Quanquan Mu1, Li Xuan1 
TL;DR: The experimental results of the adaptive optics (AO) system for retina imaging are presented to prove its feasibility for highly aberrated eyes.
Abstract: A new spot centroid detection algorithm for a Shack-Hartmann wavefront sensor (SHWFS) is experimentally investigated. The algorithm is a kind of dynamic tracking algorithm that tracks and calculates the corresponding spot centroid of the current spot map based on the spot centroid of the previous spot map, according to the strong correlation of the wavefront slope and the centroid of the corresponding spot between temporally adjacent SHWFS measurements. That is, for adjacent measurements, the spot centroid movement will usually fall within some range. Using the algorithm, the dynamic range of an SHWFS can be expanded by a factor of three in the measurement of tilt aberration compared with the conventional algorithm, more than 1.3 times in the measurement of defocus aberration, and more than 2 times in the measurement of the mixture of spherical aberration plus coma aberration. The algorithm is applied in our SHWFS to measure the distorted wavefront of the human eye. The experimental results of the adaptive optics (AO) system for retina imaging are presented to prove its feasibility for highly aberrated eyes.

19 citations

Journal ArticleDOI
TL;DR: An organic dual-wavelength surface-emitting distributed feedback (DFB) laser based on a waveguide configuration containing a holographic photo-curable polymer/liquid crystal (LC) periodic structure and two laser gain media is reported for the first time in this paper.
Abstract: An organic dual-wavelength surface-emitting distributed feedback (DFB) laser based on a waveguide configuration containing a holographic photo-curable polymer/liquid crystal (LC) periodic structure and two laser gain media is reported for the first time. In such a laser configuration, a laser dye [4-(dicyanomethylene)-2-methyl-6-(p-dimethylaminostyryl)-4H-pyran, DCM]-doped polymer/LC periodic grating was formed on the top of a semiconducting laser gain [poly(2-methoxy-5-(2′-ethyl-hexyloxy)-p-phenylenevinylene), MEH-PPV] layer. A dual-wavelength laser emission at 627.8 nm and 606.6 nm was obtained from the two different laser gain media. The working mechanism of the two lasing behaviors and the methods to modulate lasing wavelength positions are elaborated and demonstrated, which shows the potential to extend the applications of organic lasers.

17 citations

Journal ArticleDOI
Chao Li1, Mingliang Xia1, Dayu Li1, Quanquan Mu1, Li Xuan1 
TL;DR: Although the residual wavefront error after correction cannot to detected, the fundus images adequately demonstrate that the imaging system reaches the resolution of a single photoreceptor cell through the open-loop correction.
Abstract: Using the liquid crystal spatial light modulator LC-SLM as the wavefront corrector, an open-loop adaptive optics AO system for fundus imaging in vivo is constructed. Compared with the LC-SLM closed-loop AO system, the light energy efficiency is increased by a factor of 2, which is helpful for the safety of fundus illumination in vivo. In our experiment, the subjective accommodation method is used to precorrect the defocus aberration, and three subjects with different myopia 0, 3, and 5 D are tested. Although the residual wavefront error after correction cannot to detected, the fundus images adequately demonstrate that the imaging system reaches the reso- lution of a single photoreceptor cell through the open-loop correction. Without dilating and cyclopleging the eye, the continuous imaging for 8s is recorded for one of the subjects. © 2010 Society of Photo-Optical Instru-

14 citations

Journal ArticleDOI
TL;DR: An open-loop adaptive optics system for retinal imaging was constructed using a liquid crystal spatial light modulator (LC-SLM) as the wavefront compensator and high-resolution images of capillaries and photoreceptors were obtained.
Abstract: An open-loop adaptive optics (AO) system for retinal imaging was constructed using a liquid crystal spatial light modulator (LC-SLM) as the wavefront compensator. Due to the dispersion of the LC-SLM, there was only one illumination source for both aberration detection and retinal imaging in this system. To increase the field of view (FOV) for retinal imaging, a modified mechanical shutter was integrated into the illumination channel to control the size of the illumination spot on the fundus. The AO loop was operated in a pulsing mode, and the fundus was illuminated twice by two laser impulses in a single AO correction loop. As a result, the FOV for retinal imaging was increased to 1.7-deg without compromising the aberration detection accuracy. The correction precision of the open-loop AO system was evaluated in a closed-loop configuration; the residual error is approximately 0.0909λ (root-mean-square, RMS), and the Strehl ratio ranges to 0.7217. Two subjects with differing rates of myopia (-3D and -5D) were tested. High-resolution images of capillaries and photoreceptors were obtained.

13 citations


Cited by
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Journal ArticleDOI
03 Jul 2017
TL;DR: In this article, the fundamental optics of lenses and its extension to lenses made of liquid crystals (LCs) are described, namely, lenses with curved surfaces, flat gradient-index lenses and composite lenses.
Abstract: Lenses with tunable focal length play important roles in nature by helping species avoid predators and capture prey. Many practical devices mimic lens concept for imaging, sensing, and detection. This review covers fundamental optics of lenses and its extension to lenses made of liquid crystals (LCs). Three main types of LC lenses are described, namely, lenses with curved surfaces, flat gradient-index lenses and composite lenses. The review discusses advantages of LC lenses over their isotropic counterparts, challenges in their fabrication and control, as well as a variety of potential applications. We also discuss the current challenges associated with nematic LC lenses and their solutions. LC lenses are already having significant impacts on optics and optometry, and these impacts will grow with discovering new LC materials and new lens designs.

179 citations

Journal ArticleDOI
27 Dec 2012-Sensors
TL;DR: Current applications of AO imaging to a population of healthy adults and to the most frequent causes of blindness, including diabetic retinopathy, age-related macular degeneration and glaucoma are discussed.
Abstract: Adaptive optics (AO) is a technology used to improve the performance of optical systems by reducing the effects of optical aberrations. The direct visualization of the photoreceptor cells, capillaries and nerve fiber bundles represents the major benefit of adding AO to retinal imaging. Adaptive optics is opening a new frontier for clinical research in ophthalmology, providing new information on the early pathological changes of the retinal microstructures in various retinal diseases. We have reviewed AO technology for retinal imaging, providing information on the core components of an AO retinal camera. The most commonly used wavefront sensing and correcting elements are discussed. Furthermore, we discuss current applications of AO imaging to a population of healthy adults and to the most frequent causes of blindness, including diabetic retinopathy, age-related macular degeneration and glaucoma. We conclude our work with a discussion on future clinical prospects for AO retinal imaging.

94 citations

Journal ArticleDOI
TL;DR: The proposed approach effectively works with non-fluorescein fundus images and proves highly accurate and robust in complicated regions such as the central reflex, close vessels, and crossover points, despite a high level of illumination noise in the original data.

78 citations

Journal ArticleDOI
TL;DR: Independent and simultaneous manipulation of light beams of different wavelengths by a single hologram, which is displayed on a phase-only liquid crystal spatial light modulator (SLM), is demonstrated.
Abstract: We demonstrate independent and simultaneous manipulation of light beams of different wavelengths by a single hologram, which is displayed on a phase-only liquid crystal spatial light modulator (SLM). The method uses the high dynamic phase modulation range of modern SLMs, which can shift the phase of each pixel in a range between 0 up to 10π, depending on the readout wavelength. The extended phase range offers additional degrees of freedom for hologram encoding. Knowing the phase modulation properties of the SLM (i.e. the so-called lookup table) in the entire exploited wavelength range, an exhaustive search algorithm allows to combine different independently calculated 2π-holograms into a multi-level hologram with a phase range extending over several multiples of 2π. The combined multi-level hologram then reconstructs the original diffractive patterns with only small phase errors at preselected wavelengths, thus projecting the desired image fields almost without any crosstalk. We demonstrate this feature by displaying a static hologram at an SLM which is read out with an incoherent red-green-blue (RGB) beam, projecting a color image at a camera chip. This is done for both, a Fourier setup which needs a lens for image focusing, and in a "lensless" Fresnel setup, which also avoids the appearance of a focused zero-order spot in the image center. The experimentally obtained efficiency of a two-colour combination is on the order of 83% for each wavelength, with a crosstalk level between the two colour channels below 2%, whereas a three-colour combination still reaches an efficiency of about 60% and a crosstalk level below 5%.

63 citations

Journal ArticleDOI
20 May 2015
TL;DR: In this paper, a method to expand the dynamic range for a Shack-Hartmann wavefront sensor (SHWFS) is proposed, which enables an SHWFS to measure wavefronts with larger aberrations by applying holography and pattern matching technologies.
Abstract: A method to expand the dynamic range for a Shack–Hartmann wavefront sensor (SHWFS) is proposed. An SHWFS consists of a microlens array and an image sensor, and it has been widely used to measure the wavefront aberration of a lightwave in various fields. However, a very large aberrated wave cannot be correctly measured due to the finite dynamic range that depends on the diameter of each microlens. The proposed method enables an SHWFS to measure wavefronts with larger aberrations by applying holography and pattern matching technologies. For measurement of a spherical wave, the proposed method is compared with a conventional one by numerical simulations and optical experiments. Their results confirm the performance of the proposed method.

39 citations