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Mingming Zhang

Researcher at Fourth Military Medical University

Publications -  41
Citations -  1021

Mingming Zhang is an academic researcher from Fourth Military Medical University. The author has contributed to research in topics: Cardiac function curve & Autophagy. The author has an hindex of 16, co-authored 40 publications receiving 706 citations. Previous affiliations of Mingming Zhang include Xi'an Jiaotong University & University of Toronto.

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Effects of NB001 and gabapentin on irritable bowel syndrome-induced behavioral anxiety and spontaneous pain

TL;DR: Results indicate that NB001 and gabapentin may inhibit spontaneous pain and anxiety-like behaviors through different mechanisms, and that sensory and emotion related brain regions were activated at day 7 after the treatment with zymosan.
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Melatonin alleviates postinfarction cardiac remodeling and dysfunction by inhibiting Mst1.

TL;DR: Melatonin alleviates postinfarction cardiac remodeling and dysfunction by upregulating autophagy, decreasing apoptosis, and modulating mitochondrial integrity and biogenesis, and the attributed mechanism involved Mst1/Sirt1 signaling.
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Luteolin alleviates post-infarction cardiac dysfunction by up-regulating autophagy through Mst1 inhibition.

TL;DR: The protective effects of Luteolin are associated with up‐regulation of autophagy and improvement of mitochondrial biogenesis through Mst1 inhibition and reduction of cardiac enzyme and inflammatory markers release after MI.
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Postsynaptic insertion of AMPA receptor onto cortical pyramidal neurons in the anterior cingulate cortex after peripheral nerve injury

TL;DR: Nerve injury increased the postsynaptic expression of AMPAR GluA1 in pyramidal neurons in the layer V of the anterior cingulate cortex (ACC), including the corticospinal projecting neurons, and microinjection of NASPM into the ACC inhibited behavioral sensitization caused by nerve injury.
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Polydatin protects cardiomyocytes against myocardial infarction injury by activating Sirt3.

TL;DR: The protective effects of PD are associated with the up-regulation of autophagy and improvement of mitochondrial biogenesis through Sirt3 activity, which is evidenced by increased ATP content, citrate synthase activity and complexes I/II/III/IV/V activities in the cardiomyocytes subjected to MI injury.