M
Minru Liao
Researcher at University of Electronic Science and Technology of China
Publications - 1
Citations - 11
Minru Liao is an academic researcher from University of Electronic Science and Technology of China. The author has contributed to research in topics: Histone methyltransferase & Epigenetics. The author has co-authored 1 publications.
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Targeting cancer epigenetic pathways with small-molecule compounds: Therapeutic efficacy and combination therapies.
TL;DR: In this paper, a review of epigenetic pathways, small molecule inhibitors targeting DNA methyltransferase (DNMT) and small-molecule inhibitors targeting histone modification (the main regulatory targets are histone acetyltransferases (HAT), histone deacetylases (HDACs), as well as the combination strategies of the existing epigenetic therapeutic drugs and more new therapies to improve the efficacy.