M
Minsuk Hyun
Researcher at Howard Hughes Medical Institute
Publications - 26
Citations - 2226
Minsuk Hyun is an academic researcher from Howard Hughes Medical Institute. The author has contributed to research in topics: Optical fiber & Dorsal raphe nucleus. The author has an hindex of 13, co-authored 25 publications receiving 1577 citations. Previous affiliations of Minsuk Hyun include Konkuk University & Harvard University.
Papers
More filters
Journal ArticleDOI
Principles for applying optogenetic tools derived from direct comparative analysis of microbial opsins
Joanna Mattis,Kay M. Tye,Emily A. Ferenczi,Charu Ramakrishnan,Daniel J. O’Shea,Rohit Prakash,Lisa A. Gunaydin,Minsuk Hyun,Lief E. Fenno,Viviana Gradinaru,Ofer Yizhar,Ofer Yizhar,Karl Deisseroth +12 more
TL;DR: This work systematically compared microbial opsins under matched experimental conditions to extract essential principles and identify key parameters for the conduct, design and interpretation of experiments involving optogenetic techniques.
Journal ArticleDOI
Targeting cells with single vectors using multiple-feature Boolean logic
Lief E. Fenno,Joanna Mattis,Charu Ramakrishnan,Minsuk Hyun,Soo Yeun Lee,Miao He,Jason Tucciarone,Aslihan Selimbeyoglu,Andre Berndt,Logan Grosenick,Kelly A. Zalocusky,Hannah L. Bernstein,Haley M. Swanson,C. Perry,Ilka Diester,Frederick M. Boyce,Caroline E. Bass,Rachael L. Neve,Z. J. Huang,Karl Deisseroth +19 more
TL;DR: A flexible and modular approach is used to target intersectionally specified populations of inhibitory interneurons in mammalian hippocampus and neurons of the ventral tegmental area defined by both genetic and wiring properties, which may expand the application of genetically encoded interventional and observational tools for intact-systems biology.
Journal ArticleDOI
The Striatum Organizes 3D Behavior via Moment-to-Moment Action Selection
Jeffrey E. Markowitz,Jeffrey E. Markowitz,Winthrop F. Gillis,Celia Beron,Celia Beron,Shay Q. Neufeld,Shay Q. Neufeld,Keiramarie Robertson,Keiramarie Robertson,Neha D. Bhagat,Ralph E. Peterson,Emalee Peterson,Minsuk Hyun,Minsuk Hyun,Scott W. Linderman,Bernardo L. Sabatini,Bernardo L. Sabatini,Sandeep Robert Datta +17 more
TL;DR: These experiments reveal that DLS neurons systematically encode information about the identity and ordering of sub-second 3D behavioral motifs; this encoding is facilitated by fast-timescale decorrelations between the direct and indirect pathways.
Journal ArticleDOI
Molecular and anatomical organization of the dorsal raphe nucleus.
Kee Wui Huang,Nicole E Ochandarena,Adrienne C. Philson,Minsuk Hyun,Jaclyn E Birnbaum,Marcelo Cicconet,Bernardo L. Sabatini +6 more
TL;DR: This study lays out the molecular organization of distinct serotonergic and non-serotonergic subsystems of the dorsal raphe nucleus, and will facilitate the design of strategies for further dissection of the DRN and its diverse functions.
Journal ArticleDOI
Distinct Cortical-Thalamic-Striatal Circuits through the Parafascicular Nucleus.
Gil Mandelbaum,Julian Taranda,Trevor M. Haynes,Daniel Hochbaum,Daniel Hochbaum,Kee Wui Huang,Minsuk Hyun,Kannan Umadevi Venkataraju,Christoph Straub,Wengang Wang,Keiramarie Robertson,Pavel Osten,Bernardo L. Sabatini +12 more
TL;DR: In this paper, the thalamic parafascicular nucleus (PF) was found to have the highest density of striatum-projecting neurons among all sub-cortical structures.