M
Minxia Zhang
Researcher at Huazhong University of Science and Technology
Publications - 5
Citations - 4015
Minxia Zhang is an academic researcher from Huazhong University of Science and Technology. The author has contributed to research in topics: Internal medicine & Immunology. The author has an hindex of 3, co-authored 3 publications receiving 2840 citations.
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Journal ArticleDOI
Clinical and immunological features of severe and moderate coronavirus disease 2019.
Guang Chen,Di Wu,Wei Guo,Yong Cao,Da Huang,Hongwu Wang,Tao Wang,Xiaoyun Zhang,Huilong Chen,Haijing Yu,Xiaoping Zhang,Minxia Zhang,Shiji Wu,Jianxin Song,Tao Chen,Meifang Han,Shusheng Li,Xiaoping Luo,Jianping Zhao,Qin Ning +19 more
TL;DR: The SARS-CoV-2 infection may affect primarily T lymphocytes particularly CD4+T and CD8+ T cells, resulting in decrease in numbers as well as IFN-γ production, which may be of importance due to their correlation with disease severity in COVID-19.
Posted ContentDOI
A machine learning-based model for survival prediction in patients with severe COVID-19 infection
Li Yan,Hai-Tao Zhang,Jorge Goncalves,Yaru Xiao,Maolin Wang,Yan Guo,Chaoyang Sun,Xiuchuan Tang,Jin L,Minxia Zhang,Xiang Huang,Haosen Cao,Yanyan Chen,Tongxin Ren,Feng Wang,Suli Huang,Xi Tan,Niannian Huang,Bo Jiao,Yong Zhang,Ailin Luo,Laurent Mombaerts,Junyang Jin,Zhiguo Cao,Sumeng Li,Hui Xu,Ye Yuan +26 more
TL;DR: A three indices-based prognostic prediction model is able to predict the mortality risk, and present a clinical route to the recognition of critical cases from severe cases, which can help doctors with early identification and intervention, thus potentially reducing mortality.
Posted ContentDOI
Clinical and immunologic features in severe and moderate forms of Coronavirus Disease 2019
Guang Chen,Di Wu,Wei Guo,Yong Cao,Da Huang,Hongwu Wang,Tao Wang,Xiaoyun Zhang,Huilong Chen,Haijing Yu,Xiaoping Zhang,Minxia Zhang,Shiji Wu,Jianxin Song,Tao Chen,Meifang Han,Shusheng Li,Xiaoping Luo,Jianping Zhao,Qin Ning +19 more
TL;DR: The SARS-CoV-2 infection may affect primarily T lymphocytes, particularly CD4+T cells, resulting in significant decrease in number as well as IFN-γ production, which may be associated with disease severity in COVID-19.
Journal ArticleDOI
Comparison of the Performance of 24 Severe Acute Respiratory Syndrome Coronavirus 2 Antibody Assays in the Diagnosis of Coronavirus Disease 2019 Patients
Shiji Wu,Hongyan Hou,Huijun Liu,Ting Wang,Wei Wei,Minxia Zhang,Botao Yin,Min Huang,Ziyong Sun,Feng Wang +9 more
TL;DR: SARS-CoV-2 antibody assays may have an adjunct role in the diagnosis and exclusion of COVID-19, especially by using high-throughput technologies (EIAs or CLIAs), and the sensitivities of both IgG and IgM gradually increased with increase of onset time.
Journal ArticleDOI
Detection of serum human neutrophil lipocalin is an effective biomarker for the diagnosis and monitoring of children with bacterial infection.
Yun Wang,Minxia Zhang,Ming-hai Huang,Ting Wang,Wei Wei,Botao Yin,Min Huang,Peihong Yuan,Rujia Chen,Shiji Wu,Hongyan Hou +10 more
TL;DR: In this article , the diagnostic efficiency of human neutrophil lipocalin (HNL) in bacterial infections in children was investigated, and the level of HNL was decreased rapidly in patients with effective treatment, but maintained at high levels in deteriorated patients according to the clinical progression.