M
Miquel Mulero
Researcher at Rovira i Virgili University
Publications - 71
Citations - 2328
Miquel Mulero is an academic researcher from Rovira i Virgili University. The author has contributed to research in topics: Oxidative stress & Medicine. The author has an hindex of 25, co-authored 60 publications receiving 1718 citations. Previous affiliations of Miquel Mulero include Institut national de la recherche agronomique.
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Journal ArticleDOI
Molecular fingerprint similarity search in virtual screening.
Adrià Cereto-Massagué,María José Ojeda,Cristina Valls,Miquel Mulero,Santiago Garcia-Vallvé,Gerard Pujadas +5 more
TL;DR: This review focuses on commonly used fingerprint algorithms, their usage in virtual screening, and the software packages and online tools that provide these algorithms.
Journal ArticleDOI
DecoyFinder: an easy-to-use python GUI application for building target-specific decoy sets
Adrià Cereto-Massagué,Laura Guasch,Cristina Valls,Miquel Mulero,Gerard Pujadas,Santiago Garcia-Vallvé +5 more
TL;DR: To the best of the knowledge, DecoyFinder is the first application designed to build target-specific decoy sets, and it is provided as a validation on 10 DUD targets as Supplementary Table S1.
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The Light and Dark Sides of Virtual Screening: What Is There to Know?
Aleix Gimeno,María José Ojeda-Montes,Sarah Tomás-Hernández,Adrià Cereto-Massagué,Raúl Beltrán-Debón,Miquel Mulero,Gerard Pujadas,Santiago Garcia-Vallvé +7 more
TL;DR: The most common methodologies used in virtual screening workflows are reviewed in order to both introduce the inexperienced researcher to new methodologies and advise the experienced researcher on how to prevent common mistakes and the improper usage of virtual screening methodologies.
Journal ArticleDOI
Tools for in silico target fishing.
Adrià Cereto-Massagué,María José Ojeda,Cristina Valls,Miquel Mulero,Gerard Pujadas,Santiago Garcia-Vallvé +5 more
TL;DR: The different methods developed for target prediction, the bioactivity databases most frequently used by these methods, and the publicly available programs and servers that enable non-specialist users to obtain these types of predictions are described.
Journal ArticleDOI
Changes in oxidative stress parameters and neurodegeneration markers in the brain of the senescence-accelerated mice SAMP-8.
Francesc X. Sureda,Javier Gutierrez-Cuesta,Marta Romeu,Miquel Mulero,Anna M. Canudas,Antoni Camins,Jordi Mallol,Mercè Pallàs +7 more
TL;DR: Results show that, at as early as 5 months of age, SAMP-8 mice have cytological and molecular alterations indicative of neurodegeneration in the cerebral cortex and suggestive of altered control of the production of oxidative species and hyper-activation of calcium-dependent enzymes.