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Mir Wais Hosseini

Bio: Mir Wais Hosseini is an academic researcher from University of Strasbourg. The author has contributed to research in topics: Hydrogen bond & Ligand. The author has an hindex of 53, co-authored 357 publications receiving 11349 citations. Previous affiliations of Mir Wais Hosseini include Texas A&M University & Centre national de la recherche scientifique.


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TL;DR: An overview of the rational behind molecular tectonics is presented and a variety of molecular networks based on van der Waals interactions and hydrogen and coordination bonding possessing diverse connectivity and topology are discussed.
Abstract: Molecular networks in the crystalline phase are infinite periodic molecular assemblies formed under self-assembly conditions between self-complementary or complementary tectons. These millimeter-size structures may be regarded as hypermolecules formed by supramolecular synthesis using reversible intertecton interactions. Molecular tectonics, based on molecular recognition events and their iteration, is the approach dealing with design and preparation of molecular networks in the solid state. In this Account, an overview of the rational behind this approach is presented. A variety of molecular networks based on van der Waals interactions and hydrogen and coordination bonding possessing diverse connectivity and topology are discussed.

704 citations

Journal ArticleDOI
TL;DR: In this article, the 1,3-propylenediamine unit was incorporated in polyammonium macrocycles for anion-coordination chemistry, the binding of anions by organic ligands, which has been much less investigated than cation complexation.
Abstract: Anion-coordination chemistry, the binding of anions by organic ligands, has been much less investigated than cation complexation, although a multitude of new structures and properties may be expected in view of the role played by anionic species in chemical as well as in biological processes.' For instance, macropolycyclic ammonium salts yield katapinates2 and anion cryptate~;,-~ polyguanidinium and polyammonium salts act as anion complex one^;^^^ quaternary ammonium salts allow selective extraction and transport of amino acids8 and phosphate^.^ We now report the synthesis of three new polyaza macrocycles 1 [24]N6, 2 [32]N8, and 3 [27]N603, and preliminary studies of the anion-binding properties of the corresponding polyammonium salts. The 1,3-propylenediamine unit incorporated in 1 and 2 was chosen for two reasons: (1) Polyammonium salts, based on the ethylenediamine pattern, require acidic pH for full protonation but bind anions more strongly than the pH-insensitive polyguanidinium salts.' The 1,3-propylenediammonium unit should represent a compromise between these two cases. Another possibility is to isolate ethylenediamine units by longer chains, as is the case in compound 3 where three such units are spread around the macrocycle. (2) Natural polyamines like putrescine, spermidine, and spermine contain amine functions separated by three or four methylene groups; they bind strongly to nucleotides,1° and play an important role in many biological processes such as nucleic acid and protein synthesis and cell growth.\" The synthesis of 1-3 will be described very briefly. Tosylation of 1,7-diamin0-4-azaheptane yields 4, which is converted into the diol 5 (ClCH2CH2CH20H, K2C03/DMF, 100 \"C; 42% yield) and then into 6 (CH3SO2C1, Et3N, CH2C12; 97% yield); treatment of 4 with acrylonitrile in DMF gives the dinitrile 7 (80% yield) which is reduced to the diamine 8 (diborane/THF; 95% yield) and tosylated to 9 (TsCl/Et,N; 80% yield). Reaction of TsNHCH2CH20H with (C1CH2CH2)20 yields 10 (K2C0,/DMF 65% yield) which is converted successively into 11 (TsCl/pyridine; 95% yield), 12 (Gabriel reaction; 82% yield), and 13 (TsCl/H20, Et,O; 57% yield). Reaction of ethylenediamine ditosylate with ClCH2CH20CH2CH20H gives 14 (K,CO,/DMF; 80% yield) which yields 15 (TsCl/pyridine; 90% yield). The disodium salt of 4 (NaH/DMF) is condensed with 6 in DMF at 110 \"C,12 affording the macrocyclic hexatosylate 16 (mp 197-198 \"C; 50% yield). Similarly, reaction of the disodium salt of 9 with 6 gives 17, after purification on a silica column (mp 185 \"C, 35% yield). Finally, by use of 13 and 15, the macrocycle 18 is obtained (mp 126-127 OC, 65% yield). Removal of the tosyl groups of compounds 16, 17, and 18 by treatment with 30% HBr/AcOH/phenol a t 8OoC for 14 h gives

283 citations

Journal ArticleDOI
TL;DR: In this paper, the authors apply concepts developed in the context of molecular recognition of anions by synthetic receptors in solution to the design of molecular tectons capable of generating molecular networks with anionic species in the crystalline phase.

219 citations


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12 Jun 2003-Nature
TL;DR: This work has shown that highly porous frameworks held together by strong metal–oxygen–carbon bonds and with exceptionally large surface area and capacity for gas storage have been prepared and their pore metrics systematically varied and functionalized.
Abstract: The long-standing challenge of designing and constructing new crystalline solid-state materials from molecular building blocks is just beginning to be addressed with success. A conceptual approach that requires the use of secondary building units to direct the assembly of ordered frameworks epitomizes this process: we call this approach reticular synthesis. This chemistry has yielded materials designed to have predetermined structures, compositions and properties. In particular, highly porous frameworks held together by strong metal-oxygen-carbon bonds and with exceptionally large surface area and capacity for gas storage have been prepared and their pore metrics systematically varied and functionalized.

8,013 citations

Journal ArticleDOI
TL;DR: Anion recognition chemistry has grown from its beginnings with positively charged ammonium cryptand receptors for halide binding to a plethora of charged and neutral, cyclic and acyclic, inorganic and organic supramolecular host systems for the selective complexation, detection, and separation of anionic guest species.
Abstract: Anion recognition chemistry has grown from its beginnings in the late 1960s with positively charged ammonium cryptand receptors for halide binding to, at the end of the millennium, a plethora of charged and neutral, cyclic and acyclic, inorganic and organic supramolecular host systems for the selective complexation, detection, and separation of anionic guest species. Solvation effects and pH values have been shown to play crucial roles in the overall anion recognition process. More recent developments include exciting advances in anion-templated syntheses and directed self-assembly, ion-pair recognition, and the function of anions in supramolecular catalysis.

3,145 citations