M
Mireille Van Gele
Researcher at Ghent University Hospital
Publications - 59
Citations - 2788
Mireille Van Gele is an academic researcher from Ghent University Hospital. The author has contributed to research in topics: Melanoma & Merkel cell carcinoma. The author has an hindex of 29, co-authored 59 publications receiving 2537 citations. Previous affiliations of Mireille Van Gele include Ghent University.
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Journal ArticleDOI
The need for transparency and good practices in the qPCR literature
Stephen A. Bustin,Vladimir Benes,Jeremy A. Garson,Jan Hellemans,Jim F. Huggett,Mikael Kubista,Reinhold Mueller,Tania Nolan,Michael W. Pfaffl,Gregory L. Shipley,Carl T. Wittwer,Peter Schjerling,Philip J. R. Day,Mónica Abreu,Begoña Aguado,Jean-François Beaulieu,Anneleen Beckers,Sara Bogaert,John A. Browne,Fernando Carrasco-Ramiro,Liesbeth Ceelen,Kate L. Ciborowski,Pieter Cornillie,Stephanie Coulon,Ann Cuypers,Sara De Brouwer,Leentje De Ceuninck,Jurgen De Craene,Hélène De Naeyer,Ward De Spiegelaere,Kato Deckers,Annelies Dheedene,Kaat Durinck,Margarida Ferreira-Teixeira,Annelies Fieuw,Jack M. Gallup,Sandra Gonzalo-Flores,Karen Goossens,Femke Heindryckx,Elizabeth Herring,Hans Hoenicka,Laura Icardi,Rolf Jaggi,Farzad Javad,Michael Karampelias,Frederick S. B. Kibenge,Molly J. T. Kibenge,Candy Kumps,Irina Lambertz,Tim Lammens,Amelia Markey,Peter Messiaen,Evelien Mets,Sofia Morais,Alberto Mudarra-Rubio,Justine K. Nakiwala,Hilde Nelis,Pål A. Olsvik,Claudina Perez-Novo,Michelle Plusquin,Tony Remans,Ali Rihani,Paulo Rodrigues-Santos,Pieter Rondou,Rebecca Sanders,Katharina Schmidt-Bleek,Kerstin Skovgaard,Karen Smeets,Laura Tabera,Stefan Toegel,Tim Van Acker,Wim Van den Broeck,Joni Van der Meulen,Mireille Van Gele,Gert Van Peer,Mario Van Poucke,Nadine Van Roy,Sarah Vergult,Joris Wauman,Marina Tshuikina-Wiklander,Erik Willems,Sara Zaccara,Fjoralba Zeka,Jo Vandesompele +83 more
TL;DR: Two surveys of over 1,700 publications whose authors use quantitative real-time PCR (qPCR) reveal a lack of transparent and comprehensive reporting of essential technical information.
Journal ArticleDOI
Tumor formation and inactivation of RIZ1, an Rb-binding member of a nuclear protein–methyltransferase superfamily
George Steele-Perkins,George Steele-Perkins,Wei Fang,Xiao-Hong Yang,Mireille Van Gele,Tobias Carling,Jian Gu,Inge M. Buyse,Inge M. Buyse,Jonathon A. Fletcher,Jinsong Liu,Roderick T. Bronson,Robert B. Chadwick,Albert de la Chapelle,Xiao-kun Zhang,Frank Speleman,Shi Huang +16 more
TL;DR: A direct link between tumor formation and the MTase domain of RIZ1 is suggested and for the first time a tumor susceptibility gene among methyltransferases is described, involved in chromatin-mediated gene expression.
Journal ArticleDOI
Griscelli syndrome: a model system to study vesicular trafficking.
TL;DR: It is demonstrated that the identification and biological analysis of novel disease‐causing mutations highlighted the functional importance of the RAB27A‐MLPH‐MYO5A tripartite complex in intracellular melanosome transport.
Journal ArticleDOI
JAK3 as an Emerging Target for Topical Treatment of Inflammatory Skin Diseases.
Ana Karina Alves de Medeiros,Ana Karina Alves de Medeiros,Reinhart Speeckaert,Reinhart Speeckaert,Eline Desmet,Mireille Van Gele,Sofie De Schepper,Jo Lambert,Jo Lambert +8 more
TL;DR: The in vitro keratinocyte psoriasis model displayed reversal of the psoriatic JAK profile following tofacitinib treatment, indicating the need for deep skin penetration of topical JAK inhibitors in order to exert its effects on dermal immune cells.
Journal ArticleDOI
Genetic heterogeneity of neuroblastoma studied by comparative genomic hybridization
Jo Vandesompele,Nadine Van Roy,Mireille Van Gele,Genevieve Laureys,Peter F. Ambros,P. Heimann,Christine Devalck,Ed Schuuring,Penelope Brock,Jacques Otten,Jan Gyselinck,Anne De Paepe,Frank Speleman +12 more
TL;DR: The presence of 3p, 11q or 14q deletions defines a genetic subset of neuroblastomas and contributes to the further genetic characterization of stage 3 and 4 tumors without MYCN amplification (MNA) and 1p deletion.