M
Miriam Nuncia-Cantarero
Researcher at University of Castilla–La Mancha
Publications - 9
Citations - 103
Miriam Nuncia-Cantarero is an academic researcher from University of Castilla–La Mancha. The author has contributed to research in topics: Cancer & Histone methyltransferase. The author has an hindex of 4, co-authored 9 publications receiving 53 citations.
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Journal ArticleDOI
Functional transcriptomic annotation and protein–protein interaction network analysis identify NEK2, BIRC5, and TOP2A as potential targets in obese patients with luminal A breast cancer
Miriam Nuncia-Cantarero,Sandra Martinez-Canales,Fernando Andrés-Pretel,Gabriel Santpere,Alberto Ocaña,Eva María Galán-Moya +5 more
TL;DR: In silico analysis describes molecular alterations of luminal A tumors and proposes a druggable PPI network in obese patients with potential for translation to the clinical practice.
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Expression of MHC class I, HLA-A and HLA-B identifies immune-activated breast tumors with favorable outcome.
María Del Mar Noblejas-López,Cristina Nieto-Jiménez,Sara Morcillo García,Javier Pérez-Peña,Miriam Nuncia-Cantarero,Fernando Andrés-Pretel,Eva María Galán-Moya,Eitan Amir,Atanasio Pandiella,Balázs Győrffy,Alberto Ocaña +10 more
TL;DR: In the exploratory cohort, expression of HLA A and HLA-B was associated with favorable relapse-free survival (RFS) and overall survival (OS) in the basal-like subgroup and this was confirmed in the METABRIC and TCGA dataset.
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Genetic mutational status of genes regulating epigenetics: Role of the histone methyltransferase KMT2D in triple negative breast tumors.
Sara Morcillo-Garcia,María Del Mar Noblejas-López,Cristina Nieto-Jiménez,Javier Pérez-Peña,Miriam Nuncia-Cantarero,Balázs Győrffy,Eitan Amir,Atanasio Pandiella,Eva María Galán-Moya,Alberto Ocaña +9 more
TL;DR: Epigenetic modulating genes which are found to be mutated in breast cancer are described and the histone methyltransferase KMT2D, which is mutated in 6% of triple negative tumors and linked with poor survival, is identified.
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Functional transcriptomic annotation and protein–protein interaction analysis identify EZH2 and UBE2C as key upregulated proteins in ovarian cancer
Sandra Martinez-Canales,Miguel López de Rodas,Miriam Nuncia-Cantarero,Raquel Páez,Eitan Amir,Balázs Győrffy,Atanasio Pandiella,Eva María Galán-Moya,Alberto Ocaña,Alberto Ocaña +9 more
TL;DR: A set of genes overexpressed in ovarian cancer with potential for therapeutic intervention including EZH2 and UBE2C are described, identified as principal interacting proteins of druggable networks.
Journal ArticleDOI
Identification of a stemness-related gene panel associated with BET inhibition in triple negative breast cancer
Leticia Serrano-Oviedo,Miriam Nuncia-Cantarero,Sara Morcillo-Garcia,Cristina Nieto-Jiménez,Miguel Burgos,Verónica Corrales-Sánchez,Javier Pérez-Peña,Balázs Győrffy,Alberto Ocaña,Eva María Galán-Moya +9 more
TL;DR: A stemness-related gene panel associated with JQ1 is identified and how this inhibitor modifies the stemness landscape in TNBC is proposed, which could lead to less aggressive and more chemo-sensitive tumours, reflecting a better patient prognosis.