M
Mitchell A. Avery
Researcher at University of Mississippi
Publications - 259
Citations - 7897
Mitchell A. Avery is an academic researcher from University of Mississippi. The author has contributed to research in topics: Artemisinin & Docking (molecular). The author has an hindex of 46, co-authored 258 publications receiving 7539 citations. Previous affiliations of Mitchell A. Avery include University of North Dakota & Walter Reed Army Institute of Research.
Papers
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Journal ArticleDOI
Identification of Telmisartan as a Unique Angiotensin II Receptor Antagonist With Selective PPARγ–Modulating Activity
Stephen C. Benson,Harrihar A. Pershadsingh,Christopher I. Ho,Amar G. Chittiboyina,Prashant V. Desai,Michal Pravenec,N. Qi,Jiaming Wang,Mitchell A. Avery,Theodore W. Kurtz +9 more
TL;DR: In this paper, the authors showed that telmisartan, a structurally unique angiotensin II receptor antagonist used for the treatment of hypertension, can function as a partial agonist of peroxisome proliferator-activated receptor-gamma (PPARgamma) and reduce glucose, insulin, and triglyceride levels in rats fed a high-fat, high-carbohydrate diet.
Journal ArticleDOI
Antimalarial Artemisinin Drugs Induce Cytochrome P450 and MDR1 Expression by Activation of Xenosensors Pregnane X Receptor and Constitutive Androstane Receptor
Oliver Burk,Katja A. Arnold,Andreas K. Nussler,Elke Schaeffeler,Ekaterina Efimova,Bonnie A. Avery,Mitchell A. Avery,Martin F. Fromm,Michel Eichelbaum +8 more
TL;DR: Activation of PXR and CAR and especially the resulting induction of CYP3A4 and MDR1 demonstrate that artemisinin has a higher risk of potential drug interactions than anticipated previously.
Journal ArticleDOI
Stereoselective total synthesis of (+)-artemisinin, the antimalarial constituent of Artemisia annua L
Journal ArticleDOI
Physicochemical Characterization of Berberine Chloride: A Perspective in the Development of a Solution Dosage Form for Oral Delivery
Sunil Kumar Battu,Michael A. Repka,Sindhuri Maddineni,Amar G. Chittiboyina,Mitchell A. Avery,Soumyajit Majumdar +5 more
TL;DR: The physicochemical characteristics of berberine chloride and the complexation of drug with 2-hydroxypropyl-β-cyclodextrin (HPβCD) were evaluated and the feasibility of developing an oral solution dosage form of the drug was demonstrated.
Patent
1,2-dithiolane derivatives
TL;DR: In this article, the authors provided new thiazolindinedione derivatives and new arylacetic acid derivatives for the treatment of cardiovascular diseases, certain endocrine diseases, inflammatory diseases, neoplastic (malignant) and non-malignant proliferative diseases, and diseases associated with these viral infections as discussed herein.