M
Mitsuyuki Murano
Researcher at Osaka Medical College
Publications - 69
Citations - 1917
Mitsuyuki Murano is an academic researcher from Osaka Medical College. The author has contributed to research in topics: Colitis & Ulcerative colitis. The author has an hindex of 22, co-authored 69 publications receiving 1769 citations.
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Journal ArticleDOI
Present status and strategy of NSAIDs-induced small bowel injury
Kazuhide Higuchi,Eiji Umegaki,Toshio Watanabe,Yukiko Yoda,Eijiro Morita,Mitsuyuki Murano,Satoshi Tokioka,Tetsuo Arakawa +7 more
TL;DR: In the experimental model, several existing drugs for gastroduodenal ulcers prevented indomethacin-induced small intestinal injury and may be useful for preventing the adverse effects of NSAIDs not only in the stomach but also in the small intestine.
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Therapeutic effect of intracolonically administered nuclear factor kappa B (p65) antisense oligonucleotide on mouse dextran sulphate sodium (DSS)-induced colitis.
Mitsuyuki Murano,Kentaro Maemura,Hirata I,Ken Toshina,Takashi Nishikawa,Norihiro Hamamoto,S. Sasaki,Osamu Saitoh,Ken-ichi Katsu +8 more
TL;DR: Results suggest that intracolonic administration of NF‐κB antisense oligonucleotide may be effective in ulcerative colitis.
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Inhibition of dextran sulphate sodium (DSS)-induced colitis in mice by intracolonically administered antibodies against adhesion molecules (endothelial leucocyte adhesion molecule-1 (ELAM-1) or intercellular adhesion molecule-1 (ICAM-1)).
TL;DR: It is concluded that adhesion molecule expression is important in the development of DSS‐induced colitis in mice and that intracolonic administration of anti‐adhesion molecule antibodies, especially anti‐ELAM‐1 antibody, effectively inhibits the colonic inflammation.
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Comparative study of conventional colonoscopy and pan-colonic narrow-band imaging system in the detection of neoplastic colonic polyps: a randomized, controlled trial.
Takuya Inoue,Mitsuyuki Murano,Naoko Murano,Takanori Kuramoto,Ken Kawakami,Yosuke Abe,Eijiro Morita,Ken Toshina,Hideo Hoshiro,Yutaro Egashira,Eiji Umegaki,Kazuhide Higuchi +11 more
TL;DR: The pan-colonic NBI system improves the total number of adenomas detected, including significantly more diminutiveAdenomas, without prolongation of extubation time, and indicates that routine use of the NBI System for surveillance of diminutive adenoma may be recommended.
Journal ArticleDOI
Expression of the EP4 Prostaglandin E2 Receptor Subtype with Rat Dextran Sodium Sulphate Colitis: Colitis Suppression by a Selective Agonist, ONO-AE1-329
Masatoshi Nitta,Ichiro Hirata,Ken Toshina,Mitsuyuki Murano,Kentaro Maemura,Norihiro Hamamoto,S. Sasaki,Hiroaki Yamauchi,Ken-ichi Katsu +8 more
TL;DR: The results suggest that the EP4 receptor is important in colonic inflammation, and that PGE2 suppresses DSS colitis at least partly via the EP 4 receptor and the above cytokine changes.