M
Mohammed M.S. Wassel
Publications - 4
Citations - 90
Mohammed M.S. Wassel is an academic researcher. The author has contributed to research in topics: Pyrazole & Topoisomerase. The author has an hindex of 3, co-authored 3 publications receiving 32 citations.
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Novel adamantane-pyrazole and hydrazone hybridized: Design, synthesis, cytotoxic evaluation, SAR study and molecular docking simulation as carbonic anhydrase inhibitors
TL;DR: A series of pyrazole derivatives 4, 5, 6, 12, 13, 14 as well as hydrazone derivatives 7, 10, 11 were synthesized starting from adamantane-1-carbohydrazide as the bioactive core.
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Development of adamantane scaffold containing 1,3,4-thiadiazole derivatives: Design, synthesis, anti-proliferative activity and molecular docking study targeting EGFR.
Mohammed M.S. Wassel,Yousry A. Ammar,Gameel A. M. El-Hag Ali,Amany Belal,Ahmed B.M. Mehany,Ahmed Ragab +5 more
TL;DR: Thiazolo-thiadiazole adamantane derivative 17 exhibited the strongest inhibitory activity to the EGFR, which proved their role as hopeful apoptotic inducers in this research work.
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A new exploration toward adamantane derivatives as potential anti‐MDR agents: Design, synthesis, antimicrobial, and radiosterilization activity as potential topoisomerase IV and DNA gyrase inhibitors
Ahmed Ragab,Moustafa S. Abusaif,Dina S Aboul-Magd,Mohammed M.S. Wassel,G. A. M. Elhagali,Yousry A. Ammar +5 more
TL;DR: Six newly adamantane derivatives were evaluated for their antimicrobial activities against six MDR clinical pathogenic isolates and predicted that the most active derivatives had good drug‐likeness and safe properties.
Journal ArticleDOI
Antiviral Activity Of Adamantane-Pyrazole Derivatives Against Foot And Mouth Disease Virus Infection In Vivo And In Vitro With Molecular Docking Study
Mohammed M.S. Wassel,Wael M. Gamal Eldin,Ahmed Ragab,Gameel A. M. El-Hag Ali,Yousry A. Ammar +4 more
TL;DR: Results suggested that pyrazole derivatives 6a-c could be used as an effective antiviral agent against FMD virus infection.