Author
Mohammed Sultan Khuroo
Bio: Mohammed Sultan Khuroo is an academic researcher. The author has contributed to research in topics: Hepatitis A & Hepatitis. The author has an hindex of 1, co-authored 1 publications receiving 617 citations.
Topics: Hepatitis A, Hepatitis, Viral hepatitis, Hepatitis B, Hepeviridae
Papers
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TL;DR: The data strongly suggest the possibility of another human hepatitis virus and established the fecal oral route of its spread.
634 citations
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TL;DR: Findings on the genetic organization and expression strategy of HEV suggest that it is the prototype human pathogen for a new class of RNA virus or perhaps a separate genus within the Caliciviridae family.
1,016 citations
TL;DR: A large number of pathogens that are directly or indirectly transmitted by rodents are described and a simplified rodent disease model is discussed.
Abstract: Rodents are the most abundant and diversified order of living mammals in the world. Already since the Middle Ages we know that they can contribute to human disease, as black rats were associated with distribution of plague. However, also in modern times rodents form a threat for public health. In this review article a large number of pathogens that are directly or indirectly transmitted by rodents are described. Moreover, a simplified rodent disease model is discussed.
757 citations
TL;DR: Although hepatitis E was recognized as a new disease in 1980, the virus was first visualized in 1983 and its genome was cloned and characterized in 1991, the disease is probably ancient but not recognized until modern times.
646 citations
TL;DR: Patients with unexplained hepatitis should be tested for hepatitis E, whatever their age or travel history, and the source and route of infection remain uncertain, but it might be a porcine zoonosis.
Abstract: Hepatitis E is endemic in many developing countries where it causes substantial morbidity. In industrialised countries, it is considered rare, and largely confined to travellers returning from endemic areas. However, there is now a growing body of evidence that challenges this notion. Autochthonous hepatitis E in developed countries is far more common than previously recognised, and might be more common than hepatitis A. Hepatitis E has a predilection for older men in whom it causes substantial morbidity and mortality. The disease has a poor prognosis in the context of pre-existing chronic liver disease, and is frequently misdiagnosed as drug-induced liver injury. The source and route of infection remain uncertain, but it might be a porcine zoonosis. Patients with unexplained hepatitis should be tested for hepatitis E, whatever their age or travel history.
629 citations
TL;DR: It is concluded that a characteristic histological pattern exists in chronic hepatitis C, that this pattern is not always found and that prominent lymphoid follicles, though not unique to hepatitisC, provide a useful diagnostic clue.
517 citations