Monalisa Tiwari

TL;DR: The molecules considered here might be used to treat biofilm-associated infections after significant structural modifications, thereby investigating its effective delivery in the host and minimum effective concentration must be capable of eradicating biofilm infections with maximum potency without posing any adverse side effects on the host.

TL;DR: Results demonstrate that ZnO-NP could be developed as alternative therapeutics against A. baumannii, and the proposed mechanism of action of ZNO involves the production of reactive oxygen species, which elevates membrane lipid peroxidation that causes membrane leakage of reducing sugars, DNA, proteins, and reduces cell viability.

TL;DR: The active compounds of plants that have potent antibacterial activity against many bacteria including carbapenem resistant strain of A. baumannii are reviewed to help researchers involved in the screening of herbal active compounds that might act as a replacement for carbapENem.

TL;DR: A chimeric vaccine againstMultidrug-resistant Pseudomonas aeruginosa is designed with the help of comparative proteomics and reverse vaccinology approaches and Immunogenic peptides were used to design a multi-epitope vaccine construct.

TL;DR: This study has identified ZINC01155930 ((4R)-3-(cycloheptoxycarbonyl)-4-(4-etochromen-3-yl)-2-methyl-4,6,7,8-tetrahydroquinolin-5-olate) as a suitable efflux pump inhibitor worthy of further investigation in order to be used for controlling infections caused by Acinetobacter baumannii.