M
Monica Rodolfo
Researcher at University of Milan
Publications - 119
Citations - 6153
Monica Rodolfo is an academic researcher from University of Milan. The author has contributed to research in topics: Melanoma & Immunotherapy. The author has an hindex of 37, co-authored 114 publications receiving 5621 citations. Previous affiliations of Monica Rodolfo include University of Verona.
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Journal ArticleDOI
Murine dendritic cells loaded in vitro with soluble protein prime cytotoxic T lymphocytes against tumor antigen in vivo.
TL;DR: Results indicate that effector cells can be recruited and activated in vivo by antigen-pulsed DC, providing an efficient immune reaction against tumors, and that a long- lasting immunity against tumor challenge can be induced using beta-gal- pulsed bm-DC as vaccine.
Journal ArticleDOI
IDH1 mutations at residue p.R132 (IDH1(R132)) occur frequently in high-grade gliomas but not in other solid tumors.
Fonnet E. Bleeker,Simona Lamba,Sieger Leenstra,Dirk Troost,Theo J. M. Hulsebos,W. Peter Vandertop,W. Peter Vandertop,Milo Frattini,Francesca Molinari,Margaret A. Knowles,Aniello Cerrato,Monica Rodolfo,Aldo Scarpa,Lara Felicioni,Fiamma Buttitta,Sara Malatesta,Antonio Marchetti,Alberto Bardelli +17 more
TL;DR: In this paper, the authors search for mutations at position R132 of the IDH1 gene in a panel of 672 tumor samples, including high-grade glioma, gastrointestinal stromal tumors (GIST), melanoma, bladder, breast, colorectal, lung, ovarian, pancreas, prostate, and thyroid carcinoma specimens.
Journal ArticleDOI
New common variants affecting susceptibility to basal cell carcinoma
Simon N. Stacey,Patrick Sulem,Gisli Masson,Sigurjon A. Gudjonsson,Gudmar Thorleifsson,Margret Jakobsdottir,Asgeir Sigurdsson,Daniel F. Gudbjartsson,Bardur Sigurgeirsson,Kristrun R. Benediktsdottir,Kristin Thorisdottir,Rafn Ragnarsson,Dominique Scherer,Kari Hemminki,Peter Rudnai,Eugene Gurzau,Kvetoslava Koppova,Rafael Botella-Estrada,Virtudes Soriano,Pablo Juberías,Berta Saez,Yolanda Gilaberte,Victoria Fuentelsaz,Cristina Corredera,Matilde Grasa,Veronica Höiom,Annika Lindblom,Johannes J. Bonenkamp,Michelle M. van Rossum,Katja K H Aben,Esther de Vries,Mario Santinami,Maria G Di Mauro,Andrea Maurichi,Judith Wendt,Pia Hochleitner,Hubert Pehamberger,Julius Gudmundsson,Droplaug N Magnusdottir,Solveig Gretarsdottir,Hilma Holm,Valgerdur Steinthorsdottir,Michael L. Frigge,Thorarinn Blondal,Jona Saemundsdottir,Hjordis Bjarnason,Kristleifur Kristjansson,Gyda Bjornsdottir,Ichiro Okamoto,Licia Rivoltini,Monica Rodolfo,Lambertus A. Kiemeney,Johan Hansson,Eduardo Nagore,Jose I. Mayordomo,Rajesh Kumar,Margaret R. Karagas,Heather H. Nelson,Jeffrey R Gulcher,Thorunn Rafnar,Unnur Thorsteinsdottir,Jón Ólafsson,Augustine Kong,Kari Stefansson +63 more
TL;DR: It is reported conclusive evidence that rs401681[C] in the TERT-CLPTM1L locus confers susceptibility to BCC but protects against melanoma.
Journal ArticleDOI
Granulocyte colony-stimulating factor gene transfer suppresses tumorigenicity of a murine adenocarcinoma in vivo.
Mario P. Colombo,Giuliana Ferrari,Antonella Stoppacciaro,Mariella Parenza,Monica Rodolfo,Fulvio Mavilio,Giorgio Parmiani +6 more
TL;DR: Results indicate that G-CSF may have a potent antitumoral activity when released, even at low doses, at the tumor site and mediated by recruitment and targeting of neutrophilic granulocytes to G- CSF-releasing cells.
Journal ArticleDOI
pH-dependent antitumor activity of proton pump inhibitors against human melanoma is mediated by inhibition of tumor acidity.
Angelo De Milito,Rossella Canese,Maria Marino,Martina Borghi,Manuela Iero,Antonello Villa,Giulietta Venturi,Francesco Lozupone,Elisabetta Iessi,Mariantonia Logozzi,Pamela Della Mina,Mario Santinami,Monica Rodolfo,Franca Podo,Licia Rivoltini,Stefano Fais +15 more
TL;DR: Preclinical evidence supporting the use of PPI as novel therapeutic strategy for melanoma is shown, providing the proof of concept that PPI target human melanoma modifying tumor pH gradients.