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Muhammad Hassham Hassan Bin Asad

Bio: Muhammad Hassham Hassan Bin Asad is an academic researcher from COMSATS Institute of Information Technology. The author has contributed to research in topics: Medicine & Materials science. The author has an hindex of 12, co-authored 76 publications receiving 695 citations. Previous affiliations of Muhammad Hassham Hassan Bin Asad include Bahauddin Zakariya University & Kazan Federal University.


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TL;DR: The findings elaborate that CAPE is a versatile therapeutically active polyphenol and an effective adjuvant of chemotherapy for enhancing therapeutic efficacy and diminishing chemotherapy-induced toxicities.
Abstract: Caffeic acid phenethyl ester (CAPE) is a bioactive compound of propolis extract. The literature search elaborates that CAPE possesses antimicrobial, antioxidant, anti-inflammatory, and cytotoxic properties. The principal objective of this review article is to sum up and critically assess the existing data about therapeutic effects of CAPE in different disorders. The findings elaborate that CAPE is a versatile therapeutically active polyphenol and an effective adjuvant of chemotherapy for enhancing therapeutic efficacy and diminishing chemotherapy-induced toxicities.

156 citations

Journal ArticleDOI
TL;DR: Of numerous botanicals, the phenolic acids and flavonoids appear effective against UVR-induced damage; however the evidence-based studies for their anti-aging effects are still needed.
Abstract: The exposure to ultraviolet radiations (UVR) is the key source of skin sunburn; it may produce harmful entities, reactive oxygen species (ROS), leading to aging. The skin can be treated and protected from the injurious effects of ROS by using various pharmaceutical formulations, such as cream. Cream can be loaded with antioxidants to quench ROS leading to photo-protective effects. Moreover, modern medicines depend on ethnobotanicals for protection or treatment of human diseases. This review article summarizes various in vivo antioxidant studies on herbal creams loaded with phyto-extracts. These formulations may serve as cosmeceuticals to protect skin against injurious effects of UVR. The botanicals studied for dermatologic use in cream form include Acacia nilotica, Benincasa hispida, Calendula officinalis, Camellia sinensis, Camellia sinensis, Nelumbo nucifera, Capparis decidua, Castanea sativa, Coffea arabica, Crocus sativus, Emblica officinalis Gaertn, Foeniculum vulgare, Hippophae rhamnoides, Lithospermum erythrorhizon, Malus domestica, Matricaria chamomilla L., Moringa oleifera, Morus alba, Ocimum basilicum, Oryza sativa, Polygonum minus, Punica granatum, Silybum marianum, Tagetes erecta Linn., Terminalia chebula, Trigonella foenum-graecum, and Vitis vinifera. The observed anti-aging effects of cream formulations could be an outcome of a coordinating action of multiple constituents. Of numerous botanicals, the phenolic acids and flavonoids appear effective against UVR-induced damage; however the evidence-based studies for their anti-aging effects are still needed.

123 citations

Journal ArticleDOI
TL;DR: The most updated scientific literature on bioactive phytochemical and biological activities of P. corylifolia is summarized to present comprehensive and most up to date report on its ethnobotanical, ethnopharmacological, clinical,Phytochemical, and side effects.
Abstract: Psoralea corylifolia L. (Leguminosae) is a well-known traditional medicinal plant used from ancient times for treatment of various ailments. It is widely distributed and an important part of therapeutics in Ayurveda and in Chinese medicines. The aim of this review is to present comprehensive and most up to date report on its ethnobotanical, ethnopharmacological, clinical, phytochemical, and side effects. Studies on the ethnobotanical, ethnopharmacological, clinical, phytochemical, and side effects of P. corylifolia were published until year 2017 and were searched using various scientific databases. The scientific literature searched revealed that these plant species has been extensively investigated in vivo and in vitro for various biological and phytochemical studies. It has cardiotonic, vasodilator, pigmentor, antitumor, antibacterial, cytotoxic, and anti-helminthic properties and locally used for alopecia, inflammation, leukoderma, leprosy, psoriasis, and eczema. So far, about a hundred bioactive compounds have been isolated from seeds and fruits, and most important compounds identified belongs to coumarins, flavonoids, and meroterpenes groups. This review article summarized the most updated scientific literature on bioactive phytochemical and biological activities of P. corylifolia. This article will be a useful addition to providing information for future research, and more standard clinical trials are needed for the plant to be used as therapeutic agent.

95 citations

Journal ArticleDOI
TL;DR: In this article, a specific, rapid and simple UV spectrophotometric method with good sensitivity was developed and validated for the simultaneous quantification of aspirin and paracetamol in standard solutions and tablets.
Abstract: A specific, rapid and simple UV spectrophotometric method with good sensitivity was developed and validated for the simultaneous quantification of aspirin and paracetamol in standard solutions and tablets. The method employed solving of simultaneous equations based on the measurement of absorbance at two wavelengths, 265 and 257 nm, λ max for aspirin and paracetamol, respectively. The calibration curve was linear for both drugs in a concentration range of 2 to 64 µg/ml. It can be concluded from the results that present method for the simultaneous determination of aspirin and paracetamol in tablets is specific, rapid and simple with good sensitivity. This analytical method is also applicable in ordinary laboratories also. It can also be adopted for quality control tests for these drugs in tablets. Key words: UV spectrophotometric method, aspirin, paracetamol, simultaneous determination.

63 citations

Journal ArticleDOI
TL;DR: A novel compression algorithm is designed, namely, Sparse Compression Algorithm (SCA) for efficient communication, and the additively homomorphic encryption with differential privacy to prevent data from being leaked is integrated to promote communication efficiency and privacy preservation in FL.
Abstract: Artificial Intelligence (AI) has been applied to solve various challenges of real-world problems in recent years. However, the emergence of new AI technologies has brought several problems, especially with regard to communication efficiency, security threats and privacy violations. Towards this end, Federated Learning (FL) has received widespread attention due to its ability to facilitate the collaborative training of local learning models without compromising the privacy of data. However, recent studies have shown that FL still consumes considerable amounts of communication resources. These communication resources are vital for updating the learning models. In addition, the privacy of data could still be compromised once sharing the parameters of the local learning models in order to update the global model. Towards this end, we propose a new approach, namely, Federated Optimisation (FedOpt) in order to promote communication efficiency and privacy preservation in FL. In order to implement FedOpt, we design a novel compression algorithm, namely, Sparse Compression Algorithm (SCA) for efficient communication, and then integrate the additively homomorphic encryption with differential privacy to prevent data from being leaked. Thus, the proposed FedOpt smoothly trade-offs communication efficiency and privacy preservation in order to adopt the learning task. The experimental results demonstrate that FedOpt outperforms the state-of-the-art FL approaches. In particular, we consider three different evaluation criteria; model accuracy, communication efficiency and computation overhead. Then, we compare the proposed FedOpt with the baseline configurations and the state-of-the-art approaches, i.e., Federated Averaging (FedAvg) and the paillier-encryption based privacy-preserving deep learning (PPDL) on all these three evaluation criteria. The experimental results show that FedOpt is able to converge within fewer training epochs and a smaller privacy budget.

61 citations


Cited by
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08 Dec 2001-BMJ
TL;DR: There is, I think, something ethereal about i —the square root of minus one, which seems an odd beast at that time—an intruder hovering on the edge of reality.
Abstract: There is, I think, something ethereal about i —the square root of minus one. I remember first hearing about it at school. It seemed an odd beast at that time—an intruder hovering on the edge of reality. Usually familiarity dulls this sense of the bizarre, but in the case of i it was the reverse: over the years the sense of its surreal nature intensified. It seemed that it was impossible to write mathematics that described the real world in …

33,785 citations

01 Jul 1986
TL;DR: Structures in Other Domains The methodology of structural analysis discussed in this article has been applied beyond the narrow realm of natural language syntax that we have discussed in this paper, and it has been found that variation in the types of sentences that are used, whether during the course of children's acquisition of their native languages or in the centuries-long periods of linguistic change, are best characterized not as super cial and haphazard alterations, but rather in terms of parametric modi cations to the fundamental underlying grammatical rules and constraints.
Abstract: Structures in Other Domains The methodology of structural analysis discussed in this article has been applied beyond the narrow realm of natural language syntax that we have discussed in this article. Within the study of language, similar methods of analysis have been pervasively applied to the study of sounds (phonology), words (morphology), and meanings (semantics), yielding a range of of abstract structural representations whose properties bear considerable explanatory burden. There are a wealth of cases in each of these domains analogous to those discussed here, though space prevents us from going in these (see Akmajian, Demers, Farmer and Harnish 1995 for a traditional overview, and Jackendo 1994 for one more focused on connections with cognitive science). Additionally, these representations have shed substantial light on the processes of language acquisition and language change. It has been found that variation in the types of sentences that are used, whether during the course of children's acquisition of their native languages or in the centuries-long periods of linguistic change, are best characterized not as super cial and haphazard alterations, but rather in terms of parametric modi cations to the fundamental underlying grammatical rules and constraints. Moving outside the domain of language, one application of these same methods has been in the study of music cognition. Just as the representations of linguistic theory arise out of an attempt to model speakers' intuitions about well-formedness and possible meanings of the sentences of their

761 citations

Journal ArticleDOI
01 May 1949-Nature
TL;DR: The Wealth of India: A Dictionary of Indian Raw Materials and Industrial Products as mentioned in this paper is a dictionary of the economic products of India that was published during the years 1889-99 by the Government of India.
Abstract: IT may occasion some surprise to those men of science who are ill-acquainted with India, and who so frequently express the view that Governments are unappreciative of the importance of science to learn that as far back as 1886 the Government of India arranged for Dr. George (later Sir George) Watt, professor of botany in the Presidency College, Calcutta, to prepare a "Dictionary of the Economic Products of India". The six volumes of this standard work were published during the years 1889-99. In 1908 Sir George Watt published a condensed version, "The Commercial Products of India". Whatever the defects of these 'dictionaries', they have been of inestimable value to all interested in Indian natural products. The Wealth of India A Dictionary of Indian Raw Materials and Industrial Products. Raw Materials, Vol. 1. Pp. xxvii+254+39 plates. 15 rupees ; 24s. Industrial Products, Part 1. Pp. xii+182+8 plates. 8 rupees ; 12s. (New Delhi : Council of Scientific and Industrial Research, 1948.)

694 citations

Journal ArticleDOI
TL;DR: The main thrust of the book is to Hickness; as a possible therapeutic implications; as an outsider to this particuk ook, it is now breast cancer studies, I found the overall lack of orientation and linkage unsatisfactory.
Abstract: evidence showing similar craniopharyngioma and ada the jaw. I am delighted that a fifi appeared. It will remain the on the pathology of tumours system for some time yet. increased considerably in ti result it is now not so comfor and only reads with ease towards the centre of the bx truly a reference book r, \"readers\" book. ities between Congress held in Budapest during Lmantinoma of almost exclusively devoted to s steroid metabolism, their receptors th edition has effects on experimental mammary standard work and advanced human breast can of the nervous mention is made ofsome growth fa The book has main thrust of the book is to hickness; as a possible therapeutic implications. table to handle this reflects the intended readershil when opened As an outsider to this particuk ook. It is now breast cancer studies, I found 1 ather than a unsatisfactory. This was not becai presentations, which in themselves WR TIMPERLEY and well illustrated. The main de] overall lack of orientation and linkage. The briefdiscussion at the book helps no further. I suspect Practical Medical Microbiology. 13th ed. Ed JG Collee, JP Duguid, AG Fraser, BP Marmion (Pp 918; £29.50.) Churchill Livingstone. 1989. ISBN 0443-02323-8.

400 citations