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Murielle Mary-Krause

Researcher at University of Paris

Publications -  82
Citations -  6335

Murielle Mary-Krause is an academic researcher from University of Paris. The author has contributed to research in topics: Population & Cohort. The author has an hindex of 30, co-authored 72 publications receiving 5873 citations. Previous affiliations of Murielle Mary-Krause include Pierre-and-Marie-Curie University & French Institute of Health and Medical Research.

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Genetic Determinants of Response to Clopidogrel and Cardiovascular Events

TL;DR: Among patients with an acute myocardial infarction who were receiving clopidogrel, those carrying CYP2C19 loss-of-function alleles had a higher rate of subsequent cardiovascular events than those who were not, particularly marked among the patients undergoing percutaneous coronary intervention.
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Increased risk of myocardial infarction with duration of protease inhibitor therapy in HIV-infected men.

TL;DR: The results point to a duration-related effect relationship between PI and MI, with a higher MI incidence rate among men exposed to PI for 18 months or more.
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Impact of Individual Antiretroviral Drugs on the Risk of Myocardial Infarction in Human Immunodeficiency Virus-Infected Patients A Case-Control Study Nested Within the French Hospital Database on HIV ANRS Cohort CO4

TL;DR: The risk of MI was increased by cumulative exposure to all the studied PIs except saquinavir and particularly to amprenavir/fosamprenavIR with or without ritonavir, and lopinavir with ritonvir, whereas the association with abacavir cannot be considered causal.
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Increased risk of myocardial infarction in HIV-infected patients in France, relative to the general population.

TL;DR: The incidence of myocardial infarction is lower in France than in English-speaking and northern European countries, and the sex- and age-standardized morbidity ratio was estimated as 1.5 overall and 2.7 in women, by comparison with the general population.