Author
Murlidhar S. Shingare
Other affiliations: Shivaji College, Karwar
Bio: Murlidhar S. Shingare is an academic researcher from Dr. Babasaheb Ambedkar Marathwada University. The author has contributed to research in topics: Catalysis & Ionic liquid. The author has an hindex of 28, co-authored 230 publications receiving 2887 citations. Previous affiliations of Murlidhar S. Shingare include Shivaji College, Karwar.
Topics: Catalysis, Ionic liquid, Quinoline, One-pot synthesis, Aryl
Papers published on a yearly basis
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TL;DR: In this article, a one-pot synthesis of polyhydroquinoline derivatives using nanosized Nickel (Ni) as a heterogeneous catalyst has been proposed, which has promising features for the reaction response such as the shortest reaction time, excellent product yields, simple work-up procedure, and purification of products by non-chromatographic methods.
226 citations
TL;DR: In this paper, a stability indicating reversed-phase HPLC method has been developed and subsequently validated for simultaneous estimation of amlodipine (AM) present as AM besylate (AB), and benazepril hydrochloride (BH) from their combination product.
126 citations
TL;DR: In this paper, the condensation reaction of 4-oxo-(4H)-1-benzopyran-3-carbaldehydes and of aromatic aldehydes with 3-methyl-1-phenylpyrazolin-5-4H-one were carried out in an ionic liquid, ethylammonium nitrate, at room temperature in shorter times with higher yields of 78−92 and 70−75%, respectively, than found using conventional procedures.
114 citations
TL;DR: In vitro antimicrobial activities of the synthesized compounds were investigated against Gram-positive Bacillus subtilis, Gram-negative Escherichia coli and fungi Candida albicans and Aspergillus niger and some of the tested compounds showed significant antimicrobial activity.
110 citations
TL;DR: Synthesis of new 2-chloro-3-((4-phenyl-1H-1,2, 3-triazol-1-yl)methyl)quinoline derivatives (4a-h) using 1,3-dipolar cycloaddition (click chemistry) has been achieved in very high yield.
84 citations
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2,067 citations
1,326 citations
TL;DR: In this paper, the authors present an overview of the relationship between organic chemistry and natural products, focusing on the Stereochemistry and the Chemistry of Natural Products (SCHP).
Abstract: Organic Chemistry By Dr. I. L. Finar. Vol. 2: Stereochemistry and the Chemistry of Natural Products. Pp. xi + 733. (London and New York: Longmans, Green and Co., Ltd., 1956.) 40s. net.
1,037 citations
TL;DR: The present review will focus mainly on the recent literature for applications of this reaction in the field of medicinal chemistry, in particular on use of the 1,2,3-triazole moiety as pharmacophore.
Abstract: The copper(I)-catalyzed 1,2,3-triazole-forming reaction between azides and terminal alkynes has become the gold standard of 'click chemistry' due to its reliability, specificity, and biocompatibility. Applications of click chemistry are increasingly found in all aspects of drug discovery; they range from lead finding through combinatorial chemistry and target-templated in vitro chemistry, to proteomics and DNA research by using bioconjugation reactions. The triazole products are more than just passive linkers; they readily associate with biological targets, through hydrogen-bonding and dipole interactions. The present review will focus mainly on the recent literature for applications of this reaction in the field of medicinal chemistry, in particular on use of the 1,2,3-triazole moiety as pharmacophore.
983 citations
TL;DR: This work presents a meta-analysis of cycloaddition, which aims to determine the carrier and removal status of H2O through a number of mechanisms, including “catalyzed” and “pericyclic” reactions.
Abstract: 3.1.2. Huisgen [3 + 2] Cycloaddition Reaction 6313 3.1.3. Claisen Rearrangement 6315 3.2. Multicomponent Reactions 6316 3.3. Nucleophilic Ring-Opening Reactions 6316 3.4. Wittig Reaction 6318 3.5. Bioorthogonal Reactions 6318 4. Catalyzed Reactions 6319 4.1. Metal-Catalyzed Reactions 6319 4.1.1. Pericyclic Reactions 6320 4.1.2. Arylation Reactions 6321 4.1.3. Olefin Metathesis 6323 4.1.4. Mizoroki-Heck Reaction 6324 4.1.5. Suzuki Reaction 6325 4.1.6. Sonogashira Reaction 6327 4.1.7. Transfer Hydrogenation 6327 4.1.8. Lewis Acid Catalysis 6328 4.2. Organocatalyzed Reactions 6330 4.2.1. Pericyclic Reactions 6330 4.2.2. Michael Reaction 6331 4.2.3. Mannich Reaction 6332 4.2.4. Aldol Reaction 6333 5. Conclusion 6334 6. Supporting Information Available 6335 7. References 6335
928 citations