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Myron S. Cohen

Researcher at University of North Carolina at Chapel Hill

Publications -  576
Citations -  50913

Myron S. Cohen is an academic researcher from University of North Carolina at Chapel Hill. The author has contributed to research in topics: Population & Acquired immunodeficiency syndrome (AIDS). The author has an hindex of 103, co-authored 549 publications receiving 46021 citations. Previous affiliations of Myron S. Cohen include University of Massachusetts Medical School & Scripps Health.

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The detection and management of early HIV infection: A clinical and public health emergency

TL;DR: An increasing body of evidence supports the use of immediate antiretroviral therapy to treat EHI to maintain CD4 count and functionality, limit the size of the HIV reservoir, and reduce the risk of onward viral transmission.
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Management of Vaginal Discharge in Women Treated at a Jamaican Sexually Transmitted Disease Clinic: Use of Diagnostic Algorithms Versus Laboratory Testing

TL;DR: Algorithms for syndromic management of abnormal vaginal discharge were used to treat 752 women who presented at a Jamaican sexually transmitted disease (STD) clinic and the most sensitive algorithm was selected for routine use in Jamaican STD clinics.
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A Substantial Transmission Bottleneck among Newly and Recently HIV-1-Infected Injection Drug Users in St Petersburg, Russia

TL;DR: The results indicate that a single variant was transmitted in a majority of cases (9 of 13 participants), which is analogous to what is observed in sexual transmission and most consistent with a genetic bottleneck during transmission by injection drug use that is due to a small inoculum, which most often results in the transmission of a low-complexity viral population.
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Phenotypic Correlates of HIV-1 Macrophage Tropism

TL;DR: Data suggest that emergence of M-tropic HIV-1 includes multiple steps in which a phenotype of increased sensitivity to sCD4 and enhanced CD4 usage accompany subtle changes in Env conformation, which may represent evolutionary intermediates in a multistep process to macrophage tropism.