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N Babu Spoorthy

Bio: N Babu Spoorthy is an academic researcher. The author has an hindex of 1, co-authored 1 publications receiving 5 citations.

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TL;DR: This review presents an overview of the bioactive components of the Aloe genus with emphasis on their anti-diabetic potential and other pharmacological benefits, and the potential applications and constraints have been discussed.
Abstract: The therapeutic and pharmacological properties of plant bioactive constituents still continue to be the subject of many researches. Species of the Aloe genus have a history in folklore medicine and they have gained more attention over the years due to their various medicinal properties. Phytochemical studies have revealed that the Aloe species contain a number of constituents, such as polyphenols, phytosterols, polysaccharides, proteins, amino acids, chromones, and mineral elements. A comprehensive evidence-based review on the different constituents of Aloe species is needed in order to understand the benefits imparted by them. This review presents an overview of the bioactive components of the Aloe genus with emphasis on their anti-diabetic potential and other pharmacological benefits. This information will be beneficial for the advancement of new strategies of Aloe formulations with therapeutic and economical value in the near future. Furthermore, the potential applications and constraints have also been discussed so as to provide a wider prospect for research in this field for the benefit of the society.

11 citations


Cited by
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Journal ArticleDOI
TL;DR: The dark side of Aloe vera is explored and summarized, subjected to various secondary metabolites present in it, with a need to come up with some mechanism to understand and suppress the formation of such toxic compounds completely.

8 citations

Journal ArticleDOI
TL;DR: In this article, the mechanism of action of Aloe vera and its two constituents (Carbohydrates and Polypeptides) in the alleviation of diabetes in streptozotocin-induced diabetic rats through a proteomics approach was investigated.

7 citations

Journal ArticleDOI
TL;DR: In this paper, the authors evaluated the composition of lyophilisates obtained from Aloe arborescens leaf gel at the age of one to four years and found that the one-year-old leaves were characterized by the highest content of aloin A and aloenin A while the content of polyphenols including phenolic acids, was higher in the leaves of older plants.
Abstract: The aim of the study is to evaluate the composition of lyophilisates obtained from Aloe arborescens leaf gel at the age of one to four years The leaves were obtained from controlled crops, which allowed to exclude environmental factors as variables It was confirmed that the lyophilisates obtained from different years of Aloe arborescens leaf gel varied in chromatographic analyses in terms of aloin A and aloenin A content (high-performance liquid chromatography with diode-array detection HPLC-DAD, high-performance liquid chromatography with tandem mass spectrometric detection HPLC-MS/MS) Similarly, while testing the phenolic acids and the sum of polyphenols content, differences in their levels in leaf gel lyophilisates from plants of individual years were observed (spectrophotometric method UV-VIS) The lyophilisate composition analysis showed that the one-year-old leaves were characterized by the highest content of aloin A and aloenin A While the content of polyphenols, including phenolic acids, was higher in the leaves of older plants The antioxidant potential of the tested lyophilisates was assessed simultaneously Regardless of the research model used (CUPRAC, DPPH, ABTS), an antioxidant effect was noted for Aloe arborescens leaves

7 citations

Journal ArticleDOI
TL;DR: Aloe is a genus of flowering succulent plants (with above 500 species) found in the eastern Indian Ocean Islands, Madagascar, the Arabian Peninsula, and African continent as discussed by the authors and contains several phytoconstituents.

4 citations

Journal ArticleDOI
TL;DR: In this article , the authors developed novel Aloe Vera-based nanoemulsion gel containing erythromycin (AVNE) for enhanced topical bioavailability and improved wound healing process.

4 citations