Na Zhao

TL;DR: A massive anchored parallel sequencing method using next-generation sequencing to isolate and sequence HBV integrants and identified 8 genes that were recurrent target genes by HBV integration, suggesting a clonal expansion model in HCC development.

TL;DR: An integrated expression profiling and ChIP-seq analysis show that SOX2 is involved in the BMP signaling pathway, steroid metabolic process, histone modifications, and many receptor-mediated signaling pathways such as IGF1R and ITPR2 (Inositol 1,4,5-triphosphate receptor, type 2).

TL;DR: It is shown that, both in vivo and in vitro, overexpression of CHI3L1 could promote liver cancer cells growth, migration and invasion and Western blot analysis revealed that CHi3L 1 could activate TGF-β signal pathways.

TL;DR: This report found 875 and 811 known miRNA and miRNA* in glioblastoma and normal brain tissue, respectively, representing the largest characterization of the miRNAs in GBM so far, and verified the data by quantitative RT-PCR, suggesting that deep sequencing was able to capture the expression profiles of mi RNAs.

TL;DR: An analysis of the expression level of UCHL1 in several ovarian cancer cell lines correlated negatively with their cisplatin resistance levels and found that inhibition of UCHl1 promoted cell proliferation by increasing cells in S phases of cell cycle.