Nadine Krueger

TL;DR: In this article, the authors analyzed whether B.1.617 is more adept in entering cells and/or evades antibody responses, and revealed that antibody evasion may contribute to the rapid spread of this variant.

TL;DR: In this article, the authors show that SARS-CoV-2 may escape antibody responses, which has important implications for efforts to contain the pandemic, and they show that entry of UK, South Africa, and Brazil variants into human cells is susceptible to blockade by entry inhibitors and that the South Africa and Brazil variant was partially or fully resistant to antibodies used for COVID-19 treatment and was less efficiently inhibited by serum or plasma from convalescent or BNT162b2 vaccinated individuals.

TL;DR: In this paper, the authors report that mutations frequently found in the spike protein of SARS-CoV-2 from mink were mostly compatible with efficient entry into human cells and its inhibition by soluble ACE2.

TL;DR: In this article, Alpha-1-antitrypsin (AAT) was applied to nine patients with mild-to-moderate COVID-19 and the results indicated that AAT has a mechanistic role in the pathophysiology of COVID19 based on its anti-inflammatory and anti-viral activities.