N
Nadira D. Karunaweera
Researcher at University of Colombo
Publications - 122
Citations - 4064
Nadira D. Karunaweera is an academic researcher from University of Colombo. The author has contributed to research in topics: Cutaneous leishmaniasis & Population. The author has an hindex of 30, co-authored 115 publications receiving 3611 citations. Previous affiliations of Nadira D. Karunaweera include Washington University in St. Louis & University College London.
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Journal ArticleDOI
Genome-wide and fine-resolution association analysis of malaria in West Africa
Muminatou Jallow,Yik Ying Teo,Yik Ying Teo,Kerrin S. Small,Kerrin S. Small,Kirk A. Rockett,Kirk A. Rockett,Panos Deloukas,Taane G. Clark,Taane G. Clark,Katja Kivinen,Kalifa Bojang,David J. Conway,Margaret Pinder,Giorgio Sirugo,Fatou Sisay-Joof,Stanley Usen,Sarah Auburn,Sarah Auburn,Suzannah Bumpstead,Susana Campino,Susana Campino,Alison J. Coffey,Andrew Dunham,Andrew E. Fry,Angela Green,Rhian Gwilliam,Sarah E. Hunt,Michael Inouye,Anna E. Jeffreys,Alieu Mendy,Aarno Palotie,Simon C. Potter,Jiannis Ragoussis,Jane Rogers,Kate Rowlands,Elilan Somaskantharajah,Pamela Whittaker,Claire Widden,Peter Donnelly,Bryan Howie,Jonathan Marchini,Andrew P. Morris,Miguel A. Sanjoaquin,Miguel A. Sanjoaquin,Eric A. Achidi,Tsiri Agbenyega,Angela Allen,Angela Allen,Olukemi K. Amodu,Patrick H. Corran,Abdoulaye A. Djimde,Amagana Dolo,Ogobara K. Doumbo,Chris Drakeley,Sarah J. Dunstan,Jennifer Evans,Jennifer Evans,Jeremy Farrar,Deepika Fernando,Tran Tinh Hien,Rolf D. Horstmann,Muntaser E. Ibrahim,Nadira D. Karunaweera,Gilbert Kokwaro,Kwadwo A. Koram,Martha M. Lemnge,Julie Makani,Kevin Marsh,Pascal Michon,David Modiano,Malcolm E. Molyneux,Ivo Mueller,Michael Parker,Norbert Peshu,Christopher V. Plowe,Odile Puijalon,John C. Reeder,Hugh Reyburn,Eleanor M. Riley,Anavaj Sakuntabhai,Pratap Singhasivanon,Sodiomon B. Sirima,Adama Tall,Terrie E. Taylor,Mahamadou A. Thera,Marita Troye-Blomberg,Thomas N. Williams,Michael T. Wilson,Dominic P. Kwiatkowski,Dominic P. Kwiatkowski +90 more
TL;DR: These findings provide proof of principle that fine-resolution multipoint imputation, based on population-specific sequencing data, can substantially boost authentic GWA signals and enable fine mapping of causal variants in African populations.
Journal ArticleDOI
Dynamics of fever and serum levels of tumor necrosis factor are closely associated during clinical paroxysms in Plasmodium vivax malaria.
TL;DR: The measured changing levels of serum tumor necrosis factor (TNF) during paroxysms in non-immune patients infected with P. vivax malaria suggest that the rise and fall in temperature may be directly related to the periodic changes in TNF levels induced during these infections.
Journal ArticleDOI
Genomic analysis of local variation and recent evolution in Plasmodium vivax
Richard D. Pearson,Richard D. Pearson,Roberto Amato,Roberto Amato,Sarah Auburn,Olivo Miotto,Olivo Miotto,Olivo Miotto,Jacob Almagro-Garcia,Chanaki Amaratunga,Seila Suon,Sivanna Mao,Rintis Noviyanti,Hidayat Trimarsanto,Jutta Marfurt,Nicholas M. Anstey,Timothy William,Maciej F. Boni,Christiane Dolecek,Hien Tinh Tran,Nicholas J. White,Pascal Michon,Pascal Michon,Peter Siba,Livingstone Tavul,Gabrielle Harrison,Gabrielle Harrison,Alyssa E. Barry,Alyssa E. Barry,Ivo Mueller,Ivo Mueller,Marcelo U. Ferreira,Nadira D. Karunaweera,Milijaona Randrianarivelojosia,Qi Gao,Christina Hubbart,Lee Hart,Ben Jeffery,Eleanor Drury,Daniel Mead,Mihir Kekre,Susana Campino,Magnus Manske,Victoria Cornelius,Victoria Cornelius,Bronwyn MacInnis,Kirk A. Rockett,Kirk A. Rockett,Alistair Miles,Alistair Miles,Julian C. Rayner,Rick M. Fairhurst,François Nosten,François Nosten,Ric N. Price,Ric N. Price,Dominic P. Kwiatkowski,Dominic P. Kwiatkowski +57 more
TL;DR: A dynamic landscape of local evolutionary adaptation in the parasite population is demonstrated and will provide a foundation for genomic surveillance to guide effective strategies for control and elimination of P. vivax.
Journal ArticleDOI
Sri Lankan cutaneous leishmaniasis is caused by Leishmania donovani zymodeme MON-37
TL;DR: Identification of 5 isolates from 4 CL patients by enzyme analysis during 2002 showed that they were all Leishmania donovani zymodeme MON-37, the parasite which also causes visceral leishmaniasis in India and East Africa.
Journal ArticleDOI
Cytokines kill malaria parasites during infection crisis: extracellular complementary factors are essential.
T S Naotunne,Nadira D. Karunaweera,G. Del Giudice,M U Kularatne,G. E. Grau,Richard Carter,Kamini N. Mendis +6 more
TL;DR: It is demonstrated that in a simian malaria parasite (Plasmodium cynomolgi in its natural host, the toque monkey), the loss of infectivity during crisis is due to the death of circulating intraerythrocytic gametocytes mediated by crisis serum.