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Nana Adwoa Serwah Boateng

Bio: Nana Adwoa Serwah Boateng is an academic researcher from Jiangsu University. The author has contributed to research in topics: Penicillium expansum & PEAR. The author has an hindex of 7, co-authored 13 publications receiving 154 citations.

Papers
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Journal ArticleDOI
TL;DR: In this article, a review of free and bound polyphenol extraction from plant by-products is presented, which highlights the potential for use in industry, especially in pharmaceutical, nutraceutical and cosmetic applications.
Abstract: Background In recent times, research has highlighted the bioactive roles played by non-extractable polyphenols (NEP) in human health, especially from by-products of grains, fruits and vegetables. Most studies have reported on the total phenol content of samples without adequate attention paid to a major class of polyphenols referred to as NEP. This limits the scope of polyphenol studies and the extent of NEP incorporation into medicines, nutraceuticals, cosmetic and foods among other applications. Scope and approach This review introduces NEP and gives an update on recent advances in free and bound polyphenol extraction from plant by-products. Owing to the fact that most researchers are already familiar with the extraction of free polyphenols, this review emphasizes the extraction of NEP and provides a basis for the selection of appropriate techniques and applications for different plant by-product sources. It also presents suggestions for future studies into NEP extraction efficiency from complex plant sources using alternative physical approaches. Key findings and conclusions NEP from by-products have high potential for use in industry, especially in pharmaceutical, nutraceutical and cosmetic applications. To ascertain the total phenol content of extracts, both free and bound phenols must be accounted for with special attention directed at appropriate sample pretreatment and extract hydrolysis. Higher bioactive properties of NEP, coupled with their cheaper by-product sources makes them economically viable and medicinally potent. Also, structure-function relationships and the possibility to use physical means such as slow-freezing-thawing to increase hydrolytic yield of NEP is recommended.

99 citations

Journal ArticleDOI
TL;DR: Investigation of the biocontrol efficacy of the antagonistic yeast Sporidiobolus pararoseus Y16 in the control of Aspergillus niger decay, and natural decay of table grapes revealed that the enhanced gene expression and enzyme activities are the mechanisms involved in the biOControl, while the yeast outcompeted the fungus for space and nutrients.

46 citations

Journal ArticleDOI
TL;DR: The results demonstrated that the biological control ability of M. guilliermondii induced by MeJA in restraining P. expansum infection in apples significantly decreased the decay incidence and lesion diameter of apples and increased the expression levels of defense-related enzymes in apples.

42 citations

Journal ArticleDOI
TL;DR: In this article, the effect of β-glucan on the biocontrol efficacy of Cryptococcus podzolicus against blue mold decay of pears as well as the physiological mechanism and related molecular mechanism through transcriptome technology was investigated.

26 citations

Journal ArticleDOI
28 Oct 2019
TL;DR: The main differentially expressed genes (DEGs) that were identified in P. expansum were related to interaction, cell wall degradation enzymes, anti-oxidative stress, pH regulation, and effectors.
Abstract: Blue mold, caused by Penicillium expansum, is an important postharvest disease of apple, and can result in significant economic losses. The present study investigated the interaction between P. expansum and wounded apple fruit tissues during the early stages of the infection. Spores of P. expansum became activated one hour post-inoculation (hpi), exhibited swelling at 3 hpi, and the germ tubes were found entering into apple tissues at 6 hpi. RNA-seq was performed on samples of P. expansum and apple fruit tissue collected at 1, 3, and 6 hpi. The main differentially expressed genes (DEGs) that were identified in P. expansum were related to interaction, cell wall degradation enzymes, anti-oxidative stress, pH regulation, and effectors. Apple tissues responded to the presence of P. expansum by activating pathogen-associated molecular pattern (PAMP)-triggered immunity (PTI) at 1 hpi, then activated effector-triggered immunity (ETI) at 3 hpi. This research provides new information on the interaction between P. expansum and apple fruit tissue at an early stage of the infection process.

25 citations


Cited by
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01 Jan 2008
TL;DR: This work has identified the heterotrimeric velvet complex VelB/VeA/LaeA connecting light-responding developmental regulation and control of secondary metabolism in Aspergillus nidulans, which inhibits sexual reproduction as well as secondary metabolism.
Abstract: Differentiation and secondary metabolism are correlated processes in fungi that respond to light. In Aspergillus nidulans , light inhibits sexual reproduction as well as secondary metabolism. We identified the heterotrimeric velvet complex VelB/VeA/LaeA connecting light-responding developmental regulation and control of secondary metabolism. VeA, which is primarily expressed in the dark, physically interacts with VelB, which is expressed during sexual development. VeA bridges VelB to the nuclear master regulator of secondary metabolism, LaeA. Deletion of either velB or veA results in defects in both sexual fruiting-body formation and the production of secondary metabolites.

627 citations

Journal ArticleDOI
Zhan Zhang1, Wei Sang1, Lisi Xie1, Wenxi Li1, Bei Li1, Jie Li1, Hao Tian1, Zhen Yuan1, Qi Zhao1, Yunlu Dai1 
TL;DR: A novel polyphenol-based nanocomplex is designed to evoke highly efficacious cancer immunosurveillance while localizing therapy on primary tumor and to minimize systemic side effects.
Abstract: Engineering multifunctional nanoplatforms with high therapeutic benefits has become a promising strategy for intractable cancer treatment. A novel polyphenol-based nanocomplex was designed to evoke highly efficacious cancer immunosurveillance while localizing therapy on the primary tumor and to minimize systemic side effects. This nanocomplex is prepared via metal-polyphenol coordination by encapsulating a natural polyphenol, gossypol, and a newly synthesized polyphenol derivative, polyethylene glycol-Chlorin e6 (Ce6). The combination of gossypol from cotton and the photosensitizer Ce6 can induce chemotherapeutic/photodynamic immunogenic cancer cell death upon laser irradiation, which is supported by a rich maturation of dendritic cells, concentrated secretion of inflammatory cytokines, and significant inhibition of distant untreated tumors. Finally, an assistance of the programmed-cell-death ligand-1 checkpoint-blockade immunotherapy can enhance the anti-tumor immune stimulation of our nanoplatform to a higher level.

80 citations

Journal ArticleDOI
Peipei An1, Xingbin Yang1, Jia Yu1, Jianrui Qi1, Xueyan Ren1, Qingjun Kong1 
TL;DR: In this paper, the antifungal activities and mechanisms of tea tree oil (TTO) and its main components were investigated as potential substitutes for synthetic preservatives, and α-terpineol and terpene-4-ol exhibited the greatest effectiveness at inhibiting mycelium growth and spore germination.

60 citations

Journal ArticleDOI
TL;DR: The V76-12 isolate was the most effective treatment tested in reducing leaf spot disease of oil palm seedlings, due to its ability to inhibit mycelial growth in vitro, to reduce disease symptoms in vivo and in natural fields, as well as to enhance PAL, POD and PPO activities in the oil palm.

55 citations

Journal ArticleDOI
TL;DR: The results indicated that P. membranefaciens had significant biocontrol efficacy against Rhizopus rot of peaches, and this study contributes to understand the mechanisms behind the induced disease resistance of peached by antagonistic yeast, and would provide new disease control strategy by improving the defense responses of fruit against pathogens.

49 citations