Nancy Phillips

TL;DR: A mild, positive effect of phentolamine is indicated across all measures of arousal, with significant changes in self-reported lubrication and pleasurable sensations in the vagina.

TL;DR: Alprostadil's effectiveness in enhancing subjective and physiological arousal during visual sexual stimulation was supported by patient ratings and physician assessments of vaginal erythema and transudate volume and Photoplethysmography measurement of vaginal pulse amplitude was not able to demonstrate treatment sensitivity in the present study.

TL;DR: Genitourinary syndrome of menopause (GSM) refers to a collection of symptoms resulting from diminished hormonal, primarily estrogenic stimulation to the vulvovaginal or lower urinary tract and may affect up to 50% of postmenopausal women as discussed by the authors.

TL;DR: After menopause, about half of all women experience genital, sexual, and urinary symptoms associated with decreases in estrogen, termed genitourinary syndrome of menoppause, and most do not seek relief, and first-line therapies are nonhormonal vaginal lubricants and moisturizers.

TL;DR: It is estimated that 50% of women will suffer a severe form of vulvovaginal atrophy (VVA) related to menopause, and young women may temporarily present this clinical problem while receiving va...