Nancy Walker

TL;DR: It is reported that mice homozygous for a disrupted p63 gene have major defects in their limb, craniofacial and epithelial development, and results indicate that p63 is critical for maintaining the progenitor-cell populations that are necessary to sustain epithelialDevelopment and morphogenesis.

TL;DR: It is shown that mice functionally deficient for all p73 isoforms exhibit profound defects, including hippocampal dysgenesis, hydrocephalus, chronic infections and inflammation, as well as abnormalities in pheromone sensory pathways, and there is a marked divergence in the physiological functions of the p53 family members.

TL;DR: Cl cloning of the human nicotinic acetylcholine receptor α9-ortholog is presented and the identification of a new α-like subunit (α10) that shares 58% identity with α9 is identified indicating that the two subunits coassemble in a single functional receptor.

TL;DR: It is suggested that p73 forms part of an early signaling network that controls neocortical and archicortical regionalization and that an E2F1-TAp73 dependent pathway is involved in cortical patterning.

TL;DR: The anatomical location of NT-2R mRNA is discussed in relation to possible roles for this new receptor subtype, and silver grains appear to be concentrated on glia, neurons and ependymal cells, such as cell bodies of the glia-rich corpus callosum, Purkinje neurons in the cerebellum and ependi cells lining the ventricles.