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Nanda Kishore Routhu
Researcher at Emory University
Publications - 3
Citations - 122
Nanda Kishore Routhu is an academic researcher from Emory University. The author has contributed to research in topics: Neutralizing antibody & Modified vaccinia Ankara. The author has an hindex of 2, co-authored 3 publications receiving 25 citations. Previous affiliations of Nanda Kishore Routhu include Yerkes National Primate Research Center.
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Journal ArticleDOI
SARS-CoV-2 RBD trimer protein adjuvanted with Alum-3M-052 protects from SARS-CoV-2 infection and immune pathology in the lung.
Nanda Kishore Routhu,Narayanaiah Cheedarla,Venkata S. Bollimpelli,Sailaja Gangadhara,Venkata Viswanadh Edara,Lilin Lai,Anusmita Sahoo,Ayalnesh Shiferaw,Tiffany M. Styles,Katharine Floyd,Stephanie Fischinger,Caroline Atyeo,Sally Shin,Sanjeev Gumber,Shannon Kirejczyk,Kenneth H. Dinnon,Pei Yong Shi,Vineet D. Menachery,Mark A. Tomai,Christopher B. Fox,Galit Alter,Thomas H. Vanderford,Lisa E. Gralinski,Mehul S. Suthar,Rama Rao Amara +24 more
TL;DR: In this article, a trimeric form of the spike protein was developed and showed that it induces a potent neutralizing antibody response against live virus with diverse effector functions and provides protection against SARS-CoV-2 challenge in mice and rhesus macaques.
Journal ArticleDOI
A modified vaccinia Ankara vector-based vaccine protects macaques from SARS-CoV-2 infection, immune pathology, and dysfunction in the lungs.
Nanda Kishore Routhu,Narayanaiah Cheedarla,Narayanaiah Cheedarla,Sailaja Gangadhara,Sailaja Gangadhara,Venkata S. Bollimpelli,Venkata S. Bollimpelli,Arun K. Boddapati,Ayalnesh Shiferaw,Ayalnesh Shiferaw,Sheikh Abdul Rahman,Sheikh Abdul Rahman,Anusmita Sahoo,Anusmita Sahoo,Venkata Viswanadh Edara,Lilin Lai,Lilin Lai,Katharine Floyd,Katharine Floyd,Shelly Wang,Stephanie Fischinger,Caroline Atyeo,Sally Shin,Sanjeev Gumber,Shannon Kirejczyk,Joyce Cohen,Sherrie Jean,Jennifer S. Wood,Fawn Connor-Stroud,Rachelle L. Stammen,Amit A. Upadhyay,Kathryn L. Pellegrini,David C. Montefiori,Pei Yong Shi,Vineet D. Menachery,Galit Alter,Thomas H. Vanderford,Steven E. Bosinger,Steven E. Bosinger,Mehul S. Suthar,Mehul S. Suthar,Rama Rao Amara,Rama Rao Amara +42 more
TL;DR: In this article, modified vaccinia Ankara (MVA) vectors expressing membrane-anchored pre-fusion stabilized spike (mVA/S) but not secreted S1 induced strong neutralizing antibody responses against SARS-CoV-2 in mice.
Posted ContentDOI
Modified Vaccinia Ankara Based SARS-CoV-2 Vaccine Expressing Full-Length Spike Induces Strong Neutralizing Antibody Response
Nanda Kishore Routhu,Nanda Kishore Routhu,Sailaja Gangadhara,Sailaja Gangadhara,Narayanaiah Cheedarla,Narayanaiah Cheedarla,Ayalnesh Shiferaw,Ayalnesh Shiferaw,Sheikh Abdul Rahman,Sheikh Abdul Rahman,Anusmita Sahoo,Anusmita Sahoo,Pei Yong Shi,Vineet D. Menachery,Katharine Floyd,Katharine Floyd,Stephanie Fischinger,Caroline Atyeo,Galit Alter,Mehul S. Suthar,Mehul S. Suthar,Rama Rao Amara,Rama Rao Amara +22 more
TL;DR: Results demonstrate MVA/S is a potential vaccine candidate against SARS-CoV-2 infection and that was associated with induction of bronchus-associated lymphoid tissue.