Naomi Sugimori

TL;DR: Findings indicate that antigen-driven expansion of T cells is involved in the pathogenesis of AA characterized by CyA-dependent recovery of hematopoiesis, with high homology of the amino acid sequence of the CDR3 between two different patients.

TL;DR: The results indicate that the AA patient has T cells capable of killing hematopoietic cells in an HLA-DRB1*0405-restricted manner and that such cytotoxic T cells may contribute to the pathogenesis of AA.

TL;DR: The findings suggest that the PNH‐type cells in patients with BM failure are derived from single PIGA mutant haematopoietic stem cells even when their percentages are <1% and their fate depends on the proliferation and self‐maintenance properties of the individual PIG a mutants.

TL;DR: It is suggested that myelodysplastic syndrome-unclassified with del(13q) is a benign bone marrow failure subset characterized by good response to immunosuppressive therapy and a high prevalence of increased glycosylphosphatidylinositol-anchored protein-deficient cells, and should not be considered an intermediate-risk chromosomal abnormality.

TL;DR: Some patients with myelodysplastic syndrome show a marked increase in the percentage of immature platelet fraction (IPF%) despite the absence of severe thrombocytopenia, and this investigation investigated the IPF% and other laboratory findings of 51 patients recently diagnosed with MDS.