N
Nathan D. Lawson
Researcher at University of Massachusetts Medical School
Publications - 109
Citations - 16873
Nathan D. Lawson is an academic researcher from University of Massachusetts Medical School. The author has contributed to research in topics: Zebrafish & Notch signaling pathway. The author has an hindex of 58, co-authored 100 publications receiving 15165 citations. Previous affiliations of Nathan D. Lawson include National Institutes of Health & University of Massachusetts Amherst.
Papers
More filters
Journal ArticleDOI
In vivo imaging of embryonic vascular development using transgenic zebrafish.
TL;DR: It is found that the zebrafish fli1 promoter is able to drive expression of enhanced green fluorescent protein (EGFP) in all blood vessels throughout embryogenesis, and these transgenic lines allow detailed analysis of both wild type and mutant embryonic vasculature.
Journal ArticleDOI
ChIPpeakAnno: a Bioconductor package to annotate ChIP-seq and ChIP-chip data
Lihua Julie Zhu,Claude Gazin,Nathan D. Lawson,Hervé Pagès,Simon Lin,David S. Lapointe,Michael R. Green +6 more
TL;DR: ChIPpeakAnno enables batch annotation of the binding sites identified from ChIP-seq, Chip-chip, CAGE or any technology that results in a large number of enriched genomic regions within the statistical programming environment R.
Journal ArticleDOI
Notch signaling is required for arterial-venous differentiation during embryonic vascular development.
Nathan D. Lawson,Nico Scheer,Van N. Pham,Cheol-Hee Kim,Ajay B. Chitnis,José A. Campos-Ortega,Brant M. Weinstein +6 more
TL;DR: The results suggest that notch signaling is required for the proper development of arterial and venous blood vessels, and that a major role of Notch signaling in blood vessels is to repress venous differentiation within developing arteries.
Journal ArticleDOI
A Novel miRNA Processing Pathway Independent of Dicer Requires Argonaute2 Catalytic Activity
Daniel Cifuentes,Huiling Xue,David W. Taylor,Heather Patnode,Yuichiro Mishima,Yuichiro Mishima,Sihem Cheloufi,Sihem Cheloufi,E. Ma,Shrikant Mane,Gregory J. Hannon,Nathan D. Lawson,Scot A. Wolfe,Antonio J. Giraldez +13 more
TL;DR: It is proposed that Ago2-mediated cleavage of pre-miRNAs, followed by uridylation and trimming, generates functional miRNAs independently of Dicer, which suggests that other mi RNAs might also be processed in this way.
Journal ArticleDOI
sonic hedgehog and vascular endothelial growth factor Act Upstream of the Notch Pathway during Arterial Endothelial Differentiation
TL;DR: It is found that vascular endothelial growth factor acts downstream of sonic hedgehog and upstream of the Notch pathway to determine arterial cell fate, and differential effects of Vegf on developing endothelial cells are suggested.