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Nawaf Yassi

Researcher at Walter and Eliza Hall Institute of Medical Research

Publications -  130
Citations -  8271

Nawaf Yassi is an academic researcher from Walter and Eliza Hall Institute of Medical Research. The author has contributed to research in topics: Stroke & Medicine. The author has an hindex of 22, co-authored 87 publications receiving 5849 citations. Previous affiliations of Nawaf Yassi include University of Helsinki & Florey Institute of Neuroscience and Mental Health.

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Journal ArticleDOI

Endovascular Therapy for Ischemic Stroke with Perfusion-Imaging Selection

TL;DR: In patients with ischemic stroke with a proximal cerebral arterial occlusion and salvageable tissue on CT perfusion imaging, early thrombectomy with the Solitaire FR stent retriever, as compared with alteplase alone, improved reperfusion, early neurologic recovery, and functional outcome.
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Tenecteplase versus Alteplase before Thrombectomy for Ischemic Stroke

TL;DR: Tenecteplase before thrombectomy was associated with a higher incidence of reperfusion and better functional outcome than alteplase among patients with ischemic stroke treated within 4.5 hours after symptom onset.
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Efficacy and safety of nerinetide for the treatment of acute ischaemic stroke (ESCAPE-NA1): a multicentre, double-blind, randomised controlled trial.

Michael D. Hill, +776 more
- 14 Mar 2020 - 
TL;DR: Nerinetide did not improve the proportion of patients achieving good clinical outcomes after endovascular thrombectomy compared with patients receiving placebo, and this trial is registered with ClinicalTrials.gov, NCT02930018.
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Extending thrombolysis to 4·5–9 h and wake-up stroke using perfusion imaging: a systematic review and meta-analysis of individual patient data

Bruce C.V. Campbell, +267 more
- 13 Jul 2019 - 
TL;DR: Patients with ischaemic stroke 4·5-9 h from stroke onset or wake-up stroke with salvageable brain tissue who were treated with alteplase achieved better functional outcomes than did patients given placebo, and this increase in the rate of symptomatic intracerebral haemorrhage did not negate the overall net benefit of thrombolysis.
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Penumbral imaging and functional outcome in patients with anterior circulation ischaemic stroke treated with endovascular thrombectomy versus medical therapy: a meta-analysis of individual patient-level data

Bruce C.V. Campbell, +1296 more
- 01 Jan 2019 - 
TL;DR: Estimated ischaemic core volume was independently associated with functional independence and functional improvement but did not modify the treatment benefit of endovascular thrombectomy over standard medical therapy for improved functional outcome.